The influence of time sampling scheme on kinetic parameters obtained from compartmental modeling of a dynamic PET study - A Monte Carlo study Conference Paper
| Authors: | Haggstrom, I.; Larsson, A.; Axelsson, J.; Garpebring, A.; Johansson, L.; Schmidtlein, C. R.; Sorensen, J.; Karlsson, M. |
| Title: | The influence of time sampling scheme on kinetic parameters obtained from compartmental modeling of a dynamic PET study - A Monte Carlo study |
| Conference Title: | 2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record, NSS/MIC 2012 |
| Abstract: | Compartmental modeling of dynamic PET data enables quantification of tracer kinetics in vivo, through the obtained model parameters. The dynamic data is sorted into frames during or after the acquisition, with a sampling interval usually ranging from 10 s to 300 s. In this study we wanted to investigate the effect of the chosen sampling interval on kinetic parameters obtained from a 2-tissue model, in terms of bias and standard deviation, using a complete Monte Carlo simulated dynamic 18F-FLT PET study. © 2012 IEEE. |
| Keywords: | pet; gate; monte carlo; dynamic pet; compartment model; aif; flt; sampling interval; time sampling |
| Journal Title | IEEE Nuclear Science Symposium Conference Record |
| Conference Dates: | 2012 Oct 27-Nov 3 |
| Conference Location: | Anaheim, CA |
| ISBN: | 1095-7863 |
| Publisher: | IEEE |
| Location: | Anaheim, CA |
| Date Published: | 2012-01-01 |
| Start Page: | 3101 |
| End Page: | 3107 |
| Language: | English |
| DOI: | 10.1109/NSSMIC.2012.6551707 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - IEEE Nuclear Science Symposium Conference Record - IEEE Nucl. Sci. Symp. Conf. Rec. - "Conference code: 98448" - "Export Date: 4 September 2013" - "Art. No.: 6551707" - "CODEN: 85OQA" - "Sponsors: The Nuclear and Plasma Sciences Society of the; Institute of Electrical and Electronic Engineers; (IEEE NPSS)" - 29 October 2012 through 3 November 2012 - "Source: Scopus" |
