A straightforward route to functionalized trans-diels-alder motifs Journal Article
| Authors: | Lee, J. H.; Zhang, Y.; Danishefsky, S. J. |
| Article Title: | A straightforward route to functionalized trans-diels-alder motifs |
| Abstract: | A sequence consisting of a Lewis acid-catalyzed Diels-Alder reaction on a 2-halocyclohexenone, followed by reductive alkylation, provides a route to trans-fused octalinones bearing angular methyl groups with functionality corresponding to that which would have been possible from a trans-directed Diels-Alder reaction. © 2010 American Chemical Society. |
| Keywords: | unclassified drug; nonhuman; chemical structure; alkylation; catalysis; chemical reactions; diels-alder reaction; lewis acid; diels alder reaction; acids; oxidation-reduction; functionalized; functional groups; diels-alder; methyl group; reductive alkylation; 2 cyclohexenone; 2 halocyclohexenone; cyclohexenes; lewis acids |
| Journal Title: | Journal of the American Chemical Society |
| Volume: | 132 |
| Issue: | 41 |
| ISSN: | 0002-7863 |
| Publisher: | American Chemical Society |
| Date Published: | 2010-10-20 |
| Start Page: | 14330 |
| End Page: | 14333 |
| Language: | English |
| DOI: | 10.1021/ja1073855 |
| PUBMED: | 20863105 |
| PROVIDER: | scopus |
| PMCID: | PMC2974171 |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 1" - "Export Date: 20 April 2011" - "CODEN: JACSA" - "Source: Scopus" |
