The inverse electron-demand Diels-Alder reaction as a new methodology for the synthesis of (225)Ac-labelled radioimmunoconjugates Journal Article

   

Authors:	Poty, S.; Membreno, R.; Glaser, J. M.; Ragupathi, A.; Scholz, W. W.; Zeglis, B. M.; Lewis, J. S.
Article Title:	The inverse electron-demand Diels-Alder reaction as a new methodology for the synthesis of (225)Ac-labelled radioimmunoconjugates
Abstract:	The inverse electron-demand Diels-Alder reaction between tetrazine (Tz) and trans-cyclooctene (TCO) facilitates the efficient radiosynthesis of 225Ac-labelled radioimmunoconjugates in a two-step method, outperforming conventional approaches based on isothiocyanate couplings. © 2018 The Royal Society of Chemistry.
Journal Title:	Chemical Communications
Volume:	54
Issue:	21
ISSN:	1359-7345
Publisher:	Royal Society of Chemistry
Date Published:	2018-03-14
Start Page:	2599
End Page:	2602
Language:	English
DOI:	10.1039/c7cc09129j
PROVIDER:	scopus
PMCID:	PMC5843558
PUBMED:	29388990
DOI/URL:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85043476609&doi=10.1039%2fc7cc09129j&partnerID=40&md5=c640a4503b26333fba0f58f6f96bc837
Notes:	Article -- Export Date: 2 April 2018 -- Source: Scopus

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