Diels-Alder routes to angularly halogenated cis-fused bicyclic ketones: Readily accessible cyclynone intermediates Journal Article
| Authors: | Lee, J. H.; Danishefsky, S. J. |
| Article Title: | Diels-Alder routes to angularly halogenated cis-fused bicyclic ketones: Readily accessible cyclynone intermediates |
| Abstract: | We have developed an efficient Lewis acid-catalyzed Diels-Alder route to a series of cis-fused bicyclic ketones bearing quaternary halogenation at the angular position. We have also developed a Diels-Alder-based one-flask method for the regioselective preparation of TBS-protected 6-hydroxy tetralone and 5-hydroxy indanone derivatives. © 2010 Elsevier Ltd. All rights reserved. |
| Keywords: | catalysis; lewis acid; diels alder reaction; reaction analysis; stereochemistry; quantum yield; cycloaddition; halogenation; alnus; bicyclo compound; hydroxyl group; indanone derivative; ketone derivative |
| Journal Title: | Tetrahedron Letters |
| Volume: | 51 |
| Issue: | 35 |
| ISSN: | 0040-4039 |
| Publisher: | Pergamon-Elsevier Science Ltd |
| Date Published: | 2010-09-01 |
| Start Page: | 4653 |
| End Page: | 4654 |
| Language: | English |
| DOI: | 10.1016/j.tetlet.2010.06.135 |
| PROVIDER: | scopus |
| PMCID: | PMC2936481 |
| PUBMED: | 20835369 |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 1" - "Export Date: 20 April 2011" - "CODEN: TELEA" - "Source: Scopus" |
