Improved dienophilicity of nitrocycloalkenes: Prospects for the development of a trans-Diels-Alder paradigm Journal Article
| Authors: | Kim, W. H.; Jun, H. L.; Danishefsky, S. J. |
| Article Title: | Improved dienophilicity of nitrocycloalkenes: Prospects for the development of a trans-Diels-Alder paradigm |
| Abstract: | (Chemical Equation Presented) The development of an efficient and stereoselective trans-Diels-Alder paradigm is described. A central element of this transformation is the introduction of a temporary dienophilic functionality (A), which serves both to activate the substrate for Diels-Alder cycloaddtion and, through its subsequent removal, to facilitate conversion of the cis-fused cycloadducts to the trans-fused series. © 2009 American Chemical Society. |
| Keywords: | controlled study; substrate specificity; chemical reactions; chemical equations; diels alder reaction; nitrogen; stereochemistry; stereoisomerism; chemical modification; reaction time; cycloaddition; cycloadducts; diels-alder; stereo-selective; alkadiene; cycloalkene; extraction; cycloparaffins |
| Journal Title: | Journal of the American Chemical Society |
| Volume: | 131 |
| Issue: | 35 |
| ISSN: | 0002-7863 |
| Publisher: | American Chemical Society |
| Date Published: | 2009-09-09 |
| Start Page: | 12576 |
| End Page: | 12578 |
| Language: | English |
| DOI: | 10.1021/ja9058926 |
| PUBMED: | 19685875 |
| PROVIDER: | scopus |
| PMCID: | PMC2746560 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 30 November 2010" - "CODEN: JACSA" - "Source: Scopus" |
