Authors: | Vargas, H. A.; Barrett, T.; Sala, E. |
Article Title: | MRI of ovarian masses |
Abstract: | MRI provides exquisite views of the pelvic anatomy through its high spatial resolution and tissue contrast, and as such plays a key role in the work up of ovarian lesions, identifying features that distinguish benign and malignant lesions. In the case of primary tumors it enables local staging and detection of metastatic disease to help guide management options such as complex surgery or the consideration of neoadjuvant chemotherapy. Functional MRI techniques such as diffusion-weighted MRI (DW-MRI), dynamic contrast-enhanced MRI (DCE-MRI) and tumor-selective molecular imaging are currently being evaluated as possible predictive and prognostic biomarkers in the context of ovarian malignancy, and may play a larger role in routine clinical practice in the future. Herein we provide an overview of the conventional and advanced MRI techniques used to characterize ovarian masses and of the role that MR plays in the staging, treatment selection and follow up of patients with ovarian cancer. © 2012 Wiley Periodicals, Inc. |
Keywords: | primary tumor; review; cancer staging; nuclear magnetic resonance imaging; follow up; magnetic resonance imaging; cancer diagnosis; diagnostic accuracy; ovarian cancer; metastasis; ovary cancer; tumor volume; differential diagnosis; cystadenoma; vasculotropin receptor 2; false negative result; contrast enhancement; ovary tumor; granulosa cell tumor; nanoparticle; fibroma; ca 125 antigen; ovary teratoma; germ cell tumor; false positive result; diffusion weighted imaging; endometrium tumor; yolk sac tumor; dynamic contrast-enhanced mri; diffusion coefficient; vasculotropin receptor 1; endometriosis; diffusion-weighted mri; tissue characterization; permeability; gadolinium chelate; tissue perfusion; ovary polycystic disease; folate receptor; apparent diffusion coefficient; follicle cyst; thecoma; tuboovarian abscess |
Journal Title: | Journal of Magnetic Resonance Imaging |
Volume: | 37 |
Issue: | 2 |
ISSN: | 1053-1807 |
Publisher: | Wiley Blackwell |
Date Published: | 2013-02-01 |
Start Page: | 265 |
End Page: | 281 |
Language: | English |
DOI: | 10.1002/jmri.23721 |
PROVIDER: | scopus |
PUBMED: | 23355430 |
DOI/URL: | |
Notes: | --- - "Export Date: 1 March 2013" - "CODEN: JMRIF" - "Source: Scopus" |