A 2-year prospective study assessing the emotional, sexual, and quality of life concerns of women undergoing radical trachelectomy versus radical hysterectomy for treatment of early-stage cervical cancer Journal Article

   

Authors:	Carter, J.; Sonoda, Y.; Baser, R. E.; Raviv, L.; Chi, D. S.; Barakat, R. R.; Iasonos, A.; Brown, C. L.; Abu-Rustum, N. R.
Article Title:	A 2-year prospective study assessing the emotional, sexual, and quality of life concerns of women undergoing radical trachelectomy versus radical hysterectomy for treatment of early-stage cervical cancer
Abstract:	Objective: To prospectively assess and describe the emotional, sexual, and QOL concerns of women with early-stage cervical cancer undergoing radical surgery. Methods: Seventy-one women who were consented for radical trachelectomy (RT) or radical hysterectomy (RH) were enrolled preoperatively in this 2-year study; 52 women (33 RT; 19 RH) were actively followed. Patients completed self-report surveys composed of 4 empirical measures in addition to exploratory items. Data analyses for the 2 years of prospective data are presented. Results: At preoperative assessment, women choosing RH reported greater concern about cancer recurrence (x = 7.27 [scale from 0 to 10]) than women choosing RT (x = 5.66) (P = 0.008). Forty-eight percent undergoing RH compared to 8.6% undergoing RT reported having adequate "time to complete childbearing" (P < 0.001). Both groups demonstrated scores suggestive of depression (based on the CES-D scale) and distress (based on the IES scale) preoperatively; over time, however, CES-D and IES scores generally improved. Scores on the Female Sexual Functioning Inventory (FSFI) for the total sample were below the mean cut-off (26.55), suggestive of sexual dysfunction; however, the means increased from 16.79 preoperatively to 23.78 by 12 months and 22.20 at 24 months. Conclusion: Measurements of mood, distress, sexual function, and QOL did not differ significantly by surgical type, and instead reflect the challenges faced by young cervical cancer patients treated by RT or RH without adjuvant treatment. Points of vulnerability were identified in which patients may benefit from preoperative consultation or immediate postoperative support. Overall, patients improved during the first year, reaching a plateau between Year-1 and Year-2, which may reflect a new level of functioning in survivorship. © 2010 Elsevier Inc. All rights reserved.
Keywords:	adult; middle aged; cancer surgery; young adult; major clinical study; clinical trial; cancer recurrence; follow up; hysterectomy; neoplasm staging; prospective studies; quality of life; ovariectomy; clinical assessment; health survey; self report; depression; mood; sexual dysfunction; sexuality; early cancer; uterine cervix cancer; distress syndrome; intermethod comparison; gynecologic surgical procedures; rating scale; emotion; pregnancy; radical trachelectomy; uterine cervical neoplasms; emotions; sexual function; radical hysterectomy; adjustment; center for epidemiological studies depression scale; impact of events scale; sexual dysfunctions, psychological; female sexual function index; functional assessment of cancer therapy; uterus surgery; sexual dysfunction, physiological
Journal Title:	Gynecologic Oncology
Volume:	119
Issue:	2
ISSN:	0090-8258
Publisher:	Elsevier Inc.
Date Published:	2010-11-01
Start Page:	358
End Page:	365
Language:	English
DOI:	10.1016/j.ygyno.2010.07.016
PUBMED:	20817227
PROVIDER:	scopus
PMCID:	PMC4847134
DOI/URL:	http://www.scopus.com/inward/record.url?eid=2-s2.0-77957749284&partnerID=40&md5=69998134f9cc253a8c8f00587fd7436c
Notes:	--- - "Cited By (since 1996): 3" - "Export Date: 20 April 2011" - "CODEN: GYNOA" - "Source: Scopus"

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