Gynecologic cancer treatment and the impact of cancer-related infertility Journal Article


Authors: Carter, J.; Rowland, K.; Chi, D.; Brown, C.; Abu Rustum, N.; Castiel, M.; Barakat, R.
Article Title: Gynecologic cancer treatment and the impact of cancer-related infertility
Abstract: Objective. The objective of this study was to empirically assess the emotional and sexual impact of cancer-related infertility in women with a history of gynecologic cancer. Method. Women with a history of gynecologic cancer were approached during their gynecologic oncology clinic appointment; they were provided a description of the study and asked to participate. All participants completed a one-time self-report survey. We present data acquired via the following methods: Center for Epidemiologic Studies-Depression Scale (CES-D), Impact of Events Scale (IES), Modified Inventory of Traumatic Grief (M-ITG), Female Sexual Function Index (FSFI), and the Menopausal Symptom Checklist. Results. The study sample consisted of 20 women, ages 27 to 49 years (mean, ∼40 years), who had undergone treatment for cervical (40%), ovarian (20%), or uterine (40%) cancer. Forty percent of the sample reported depressive symptoms as measured by the CES-D, with 35% of the women experiencing moderate to severe levels of distress as measured by the IES. The women in this sample experienced dissatisfaction with their overall sex lives (67%), pain during vaginal penetration (62%), and low levels of sexual desire (56%). Conclusions. The preliminary findings of this study indicated that feelings of depression, grief, stress, and sexual dysfunction are being experienced by women with a history of gynecologic cancer who have lost their fertility as a result of their cancer treatment. © 2004 Elsevier Inc. All rights reserved.
Keywords: adult; cancer chemotherapy; clinical article; middle aged; cancer surgery; antineoplastic agent; ovary cancer; pain; cancer therapy; infertility; self report; questionnaires; genital neoplasms, female; depression; sexual dysfunction; uterine cervix cancer; gynecologic surgical procedures; rating scale; cross-sectional studies; uterus cancer; gynecologic cancer; sexual function; sexual intercourse; infertility, female; sexual behavior; menopausal syndrome; sexual; gynecologic; emotional
Journal Title: Gynecologic Oncology
Volume: 97
Issue: 1
ISSN: 0090-8258
Publisher: Elsevier Inc.  
Date Published: 2005-04-01
Start Page: 90
End Page: 95
Language: English
DOI: 10.1016/j.ygyno.2004.12.019
PUBMED: 15790443
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 54" - "Export Date: 24 October 2012" - "CODEN: GYNOA" - "Source: Scopus"
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MSK Authors
  1. Richard R Barakat
    629 Barakat
  2. Carol Brown
    167 Brown
  3. Dennis S Chi
    710 Chi
  4. Mercedes Castiel
    18 Castiel
  5. Jeanne Carter
    160 Carter