The role of antioxidants in photoprotection: A critical review Journal Article
| Authors: | Chen, L.; Hu, J. Y.; Wang, S. Q. |
| Article Title: | The role of antioxidants in photoprotection: A critical review |
| Abstract: | Free radicals have long been studied as a contributor to aging and disease processes. Endogenous production of radicals from cellular metabolism and exogenous sources from ultraviolet radiation and pollution can damage the skin on the cellular and tissue levels. Although the body possesses an elegant defense system to prevent radical damage, this innate system can be overwhelmed and lead to a state of oxidative stress or immunosuppression, and can even trigger carcinogenesis. Topical supplementation of antioxidants can provide additional protection to neutralize reactive oxygen species from both endogenous and exogenous sources. This review will discuss our current understanding of the mechanisms of free radical damage and evaluate the potential benefit of topical antioxidants in sunscreens and skin care products. Copyright © 2012 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved. |
| Keywords: | review; animal; metabolism; animals; physiology; reactive oxygen species; reactive oxygen metabolite; antioxidant; oxidative stress; antioxidants; alpha tocopherol; ascorbic acid; immunosuppressive treatment; mitochondria; lipid peroxidation; mitochondrion; sunlight; immunosuppression; skin aging; vitamin e; free radicals; cutaneous parameters; free radical |
| Journal Title: | Journal of the American Academy of Dermatology |
| Volume: | 67 |
| Issue: | 5 |
| ISSN: | 0190-9622 |
| Publisher: | Mosby Elsevier |
| Date Published: | 2012-11-01 |
| Start Page: | 1013 |
| End Page: | 1024 |
| Language: | English |
| PUBMED: | 22406231 |
| PROVIDER: | scopus |
| DOI: | 10.1016/j.jaad.2012.02.009 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 1 February 2013" - "Source: Scopus" |
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