In vivo magnetic resonance spectroscopic imaging and ex vivo quantitative neuropathology by high resolution magic angle spinning proton magnetic resonance spectroscopy Journal Article


Authors: Simões, R. V.; Candiota, A. P.; Julià-Sapé, M.; Arús, C.
Article Title: In vivo magnetic resonance spectroscopic imaging and ex vivo quantitative neuropathology by high resolution magic angle spinning proton magnetic resonance spectroscopy
Abstract: The applications of two magnetic resonance techniques to the study of brain tumours are discussed. Multivoxel MR spectroscopic imaging (MRSI) can be performed in vivo in animal models and HRMAS is performed ex vivo. The first one is able to provide molecular images of tumours and the second one gives rich metabolomic information from excised biopsies. The application of both techniques yields a high amount of multidimensional data, which can be analysed with complex statistical methods, such as those provided by pattern recognition techniques. © 2013 Springer Science+Business Media New York.
Keywords: glioblastoma; magnetic resonance spectroscopic imaging; magnetic resonance spectroscopy; pattern recognition; brain tumours; high resolution magic angle spinning proton magnetic resonance spectroscopy
Journal Title: Neuromethods
Volume: 77
ISSN: 0893-2336
Publisher: Springer Science + Business Media, LLC  
Date Published: 2013-01-01
Start Page: 329
End Page: 365
Language: English
DOI: 10.1007/7657_2011_31
PROVIDER: scopus
DOI/URL:
Notes: Chapter 17 in "Animal Models of Brain Tumors" (ISBN: 978-1-62703-208-7) -- "Source: Scopus"
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  1. Rui Vasco Portas Ferreira Simoes
    6 Simoes