High-field small animal magnetic resonance oncology studies Journal Article

   


Authors: Bokacheva, L.; Ackerstaff, E.; LeKaye, H. C.; Zakian, K.; Koutcher, J. A.
Article Title: High-field small animal magnetic resonance oncology studies
Abstract: This review focuses on the applications of high magnetic field magnetic resonance imaging (MRI) and spectroscopy (MRS) to cancer studies in small animals. High-field MRI can provide information about tumor physiology, the microenvironment, metabolism, vascularity and cellularity. Such studies are invaluable for understanding tumor growth and proliferation, response to treatment and drug development. The MR techniques reviewed here include 1H, 31P, chemical exchange saturation transfer imaging and hyperpolarized 13C MRS as well as diffusion-weighted, blood oxygen level dependent contrast imaging and dynamic contrast-enhanced MRI. These methods have been proven effective in animal studies and are highly relevant to human clinical studies. © 2014 Institute of Physics and Engineering in Medicine.
Journal Title: Physics in Medicine and Biology
Volume: 59
Issue: 2
ISSN: 0031-9155
Publisher: IOP Publishing Ltd  
Date Published: 2014-01-01
Start Page: R65
End Page: R127
Language: English
DOI: 10.1088/0031-9155/59/2/r65
PROVIDER: scopus
PUBMED: 24374985
PMCID: PMC4389287
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-84896360390&partnerID=40&md5=985d66a11bdac4e17cc02f25bb3c4691
Notes: Export Date: 2 April 2014 -- CODEN: PHMBA -- Source: Scopus
Altmetric
What is Altmetric?
Citation Impact
What is Dimensions Citation Badge?
BMJ Impact Analytics
MSK Authors
  1. Hongbiao Carl Lekaye
    32 Lekaye
  2. Kristen L Zakian
    82 Zakian
  3. Jason A Koutcher
    278 Koutcher
  4. Louisa Bokacheva
    7 Bokacheva
  5. Ellen Ackerstaff
    43 Ackerstaff
Related MSK Work