Extraneural ependymoma: Distant bone, lung, liver, and lymph node metastases following bevacizumab Journal Article
| Authors: | Fischer, C.; Haque, S. S.; Huse, J. T.; Blochin, E.; Souweidane, M. M.; Lis, E.; Khakoo, Y. |
| Article Title: | Extraneural ependymoma: Distant bone, lung, liver, and lymph node metastases following bevacizumab |
| Abstract: | Extraneural metastases of ependymoma are rare, and have been reported in the lungs, lymph nodes, pleura, mediastinum, liver, diaphragmatic muscle, and bone. We report a case of anaplastic ependymoma with distant metastases to the vertebral bones, lungs, liver, and lymph nodes following treatment with bevacizumab. Recent research has hypothesized that angiogenic tumors may develop means of resistance to antiangiogenic therapies, and some evidence suggests potential for antiangiogenic therapies to promote additional means for cancer spread. Nevertheless, antiangiogenic therapies continue to demonstrate potential as potent therapies for the treatment of many cancers, and should continue to be researched for future uses. © 2012 Wiley Periodicals, Inc. |
| Keywords: | cancer chemotherapy; child; human tissue; preschool child; case report; bevacizumab; drug withdrawal; bone metastasis; nuclear magnetic resonance imaging; lymph node metastasis; computer assisted tomography; angiogenesis; oncology; distant metastasis; irinotecan; liver metastasis; lung metastasis; tamoxifen; ependymoma; headache; antibodies; developmental disorder; drug substitution; brain biopsy; hemiparesis; rare disease; brain tumors; focal epilepsy; macrocephaly |
| Journal Title: | Pediatric Blood and Cancer |
| Volume: | 60 |
| Issue: | 1 |
| ISSN: | 1545-5009 |
| Publisher: | Wiley Periodicals, Inc |
| Date Published: | 2013-01-01 |
| Start Page: | 143 |
| End Page: | 145 |
| Language: | English |
| DOI: | 10.1002/pbc.24268 |
| PROVIDER: | scopus |
| PUBMED: | 22976578 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 2 January 2013" - "CODEN: PBCEA" - "Source: Scopus" |
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