A clinical oncologic perspective on breast magnetic resonance imaging Journal Article
| Authors: | Bloom, S.; Morrow, M. |
| Article Title: | A clinical oncologic perspective on breast magnetic resonance imaging |
| Abstract: | Magnetic resonance (MR) imaging identifies cancer not found by clinical examination or other breast imaging studies, but its effect on patient outcomes is controversial. To date, its use has not been shown to increase the likelihood of obtaining negative surgical margins, decrease the rate of conversion from lumpectomy to mastectomy, or decrease local recurrence. The rate of tumor identification with MR imaging is 2 to 3 times higher than the incidence of local recurrence, resulting in mastectomies that may not be beneficial to the patient. This is also a concern with the use of MR imaging for contralateral cancer detection. The use of MR imaging for early detection of local recurrence does not take into account what is known about the biology of local recurrence because a short interval to local recurrence is associated with poor prognosis. In problem areas, such as evaluation of response to neoadjuvant therapy and detection of cancer presenting as axillary adenopathy, MR imaging provides information that is useful for clinical management. © 2010 Elsevier Inc. |
| Keywords: | overall survival; clinical trial; review; cancer recurrence; doxorubicin; patient selection; cancer adjuvant therapy; disease free survival; neoadjuvant therapy; nuclear magnetic resonance imaging; magnetic resonance imaging; lymph node dissection; preoperative evaluation; sensitivity and specificity; multiple cycle treatment; neoplasm recurrence, local; breast cancer; mastectomy; tumor volume; cyclophosphamide; breast neoplasms; docetaxel; cancer invasion; mammography; breast examination; partial mastectomy; reoperation; tamoxifen; neoplasms, second primary; trastuzumab; false positive result; intraductal carcinoma; neoplasms, multiple primary; mastectomy, segmental; breast biopsy; ultrasonography, mammary; breast-conserving therapy; occult cancer; local recurrence; bilateral cancer |
| Journal Title: | Magnetic Resonance Imaging Clinics of North America |
| Volume: | 18 |
| Issue: | 2 |
| ISSN: | 1064-9689 |
| Publisher: | W.B. Saunders Co-Elsevier Inc. |
| Date Published: | 2010-05-01 |
| Start Page: | 277 |
| End Page: | 294 |
| Language: | English |
| DOI: | 10.1016/j.mric.2010.02.007 |
| PUBMED: | 20494312 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 1" - "Export Date: 20 April 2011" - "CODEN: MRIAF" - "Source: Scopus" |
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