Authors: | Biermann, J. S.; Baker, L. H.; Benjamin, R.; Brigman, B.; Chow, W.; Conrad, E. U. 3rd; Frassica, D.; Frassica, F. J.; George, S.; Healey, J. H.; Heck, R.; Letson, G. D.; Mayerson, J.; Neff, J.; O'Donnell, R. J.; Randall, R. L.; Santana, V.; Satcher, R. L.; Schmidt, R. G.; Siegel, H. J.; Wong, M. K.; Yasko, A. W. |
Article Title: | Bone cancer: Clinical practice guidelines in oncology |
Abstract: | Primary bone cancers are extremely uncommon, comprise many different types with wide clinical heterogeneity, and are often curable when treated properly. There are many different kinds of primary bone cancers, and the names are principally based on histologic origin. For certain sarcomas, the cell type of origin has not yet been specifically determined. The three most common primary bone sarcomas are osteosarcoma (35%), chondrosarcoma (30%), and the Ewing's family of tumors (16%). Today, approximately three quarters of all newly diagnosed patients with osteosarcoma are cured. Of adult patients with osteosarcoma, nearly 95% can be treated successfully with limb-salvage approaches rather than amputation. Similar cure rates are associated with the Ewing's family of tumors, and in both osteosarcoma and Ewing's, cure is still achievable, even when lung metastasis occurs. © Journal of the National Comprehensive Cancer Network. |
Keywords: | osteosarcoma; bone neoplasms; cancer surgery; limb salvage; clinical trial; review; cisplatin; doxorubicin; cancer adjuvant therapy; cancer radiotherapy; methotrexate; cancer staging; drug megadose; cancer diagnosis; neoplasm staging; carboplatin; metastasis; etoposide; nccn clinical practice guidelines; cyclophosphamide; vincristine; practice guideline; ifosfamide; ewing sarcoma; sarcoma; folinic acid; medical society; medical practice; surgery; cancer relapse; radiation therapy; dermatofibroma; chondrosarcoma; bone cancer; teamwork; chondrosarcomas; osteosarcomas; bone biopsy; fibrosarcomas; ameloblastoma |
Journal Title: | Journal of the National Comprehensive Cancer Network |
Volume: | 3 |
Issue: | 2 |
ISSN: | 1540-1405 |
Publisher: | Harborside Press |
Date Published: | 2005-03-01 |
Start Page: | 124 |
End Page: | 140 |
Language: | English |
PUBMED: | 19817025 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | --- - "Export Date: 24 October 2012" - "Source: Scopus" |