Distant metastases from head and neck squamous cell carcinoma. Part III. Treatment Journal Article
| Authors: | Haigentz, M. Jr; Hartl, D. M.; Silver, C. E.; Langendijk, J. A.; Strojan, P.; Paleri, V.; De Bree, R.; MacHiels, J. P.; Hamoir, M.; Rinaldo, A.; Paccagnella, D.; Shaha, A. R.; Takes, R. P.; Ferlito, A. |
| Article Title: | Distant metastases from head and neck squamous cell carcinoma. Part III. Treatment |
| Abstract: | Distant metastases from head and neck squamous cell carcinoma (HNSCC), though rare at initial presentation, remain an important manifestation of cancer recurrence and mortality. Although generally considered incurable with a dismal prognosis despite palliative therapy, highly selected patients with distant metastases may have a long term survival benefit from aggressive surgery or radiotherapy. Advances in systemic treatments also may improve patient survival. This article reviews the current state of management of HNSCC patients with distant metastases. © 2012 Elsevier Ltd. All rights reserved. |
| Keywords: | cancer chemotherapy; cancer survival; cancer surgery; overall survival; review; cancer recurrence; cisplatin; fluorouracil; bone metastasis; paclitaxel; cancer radiotherapy; chemotherapy; treatment; methotrexate; cancer palliative therapy; carboplatin; quality of life; cetuximab; cancer mortality; distant metastasis; ifosfamide; panitumumab; liver metastasis; lung metastasis; brain metastasis; skin metastasis; metastasectomy; distant metastases; head and neck squamous cell carcinoma; metastasis resection; long term survival |
| Journal Title: | Oral Oncology |
| Volume: | 48 |
| Issue: | 9 |
| ISSN: | 1368-8375 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2012-09-01 |
| Start Page: | 787 |
| End Page: | 793 |
| Language: | English |
| DOI: | 10.1016/j.oraloncology.2012.03.019 |
| PROVIDER: | scopus |
| PUBMED: | 22516376 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 1 October 2012" - "CODEN: EJCCE" - "Source: Scopus" |
