Current status of FDG-PET for head and neck cancer Journal Article
| Author: | Wong, R. J. |
| Article Title: | Current status of FDG-PET for head and neck cancer |
| Abstract: | 18-FDG-PET has utility for the identification of the unknown primary head and neck squamous carcinoma, distant metastases or second primary carcinomas, and recurrent HNSCC in the post-treatment setting. PET has a high negative predictive value in the detection of recurrent HNSCC. Standardized uptake values have demonstrated prognostic value. Limitations of PET include a lower utility for identifying occult nodal metastases and false positive readings from inflammation, infection, muscle activity, and radiation effect. Novel radioactive tracers may enable PET to identify sites of DNA replication, protein metabolism, and hypoxia. © 2008 Wiley-Liss, Inc. |
| Keywords: | clinical trial; review; cancer recurrence; intensity modulated radiation therapy; squamous cell carcinoma; radiation dose; nuclear magnetic resonance imaging; positron emission tomography; follow up; lymph node metastasis; cancer diagnosis; diagnostic accuracy; laboratory diagnosis; sensitivity and specificity; radiopharmaceuticals; dna synthesis; tumor localization; computer assisted tomography; infection; neoplasm recurrence, local; inflammation; hypoxia; drug accumulation; head and neck cancer; head and neck neoplasms; fdg-pet; fluorodeoxyglucose f 18; fluorodeoxyglucose f18; positron-emission tomography; neoplasm metastasis; radiopharmaceutical agent; intermethod comparison; 1 fluoro 3 (2 nitro 1 imidazolyl) 2 propanol f 18; radiotherapy planning, computer-assisted; neoplasms, second primary; head and neck; mouth carcinoma; functional imaging; methionine c 11; carbon 11; fluorothymidine f 18; oxygen 15; nitrogen 13 |
| Journal Title: | Journal of Surgical Oncology |
| Volume: | 97 |
| Issue: | 8 |
| ISSN: | 0022-4790 |
| Publisher: | Wiley Blackwell |
| Date Published: | 2008-06-15 |
| Start Page: | 649 |
| End Page: | 652 |
| Language: | English |
| DOI: | 10.1002/jso.21018 |
| PUBMED: | 18493944 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 23" - "Export Date: 17 November 2011" - "CODEN: JSONA" - "Source: Scopus" |
