Authors: | Cooper, D. S.; Doherty, G. M.; Haugen, B. R.; Kloos, R. T.; Lee, S. L.; Mandel, S. J.; Mazzaferri, E. L.; McIver, B.; Pacini, F.; Schlumberger, M.; Sherman, S. I.; Steward, D. L.; Tuttle, R. M. |
Article Title: | Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer |
Abstract: | Background: Thyroid nodules are a common clinical problem, and differentiated thyroid cancer is becoming increasingly prevalent. Since the publication of the American Thyroid Association's guidelines for the management of these disorders was published in 2006, a large amount of new information has become available, prompting a revision of the guidelines. Methods: Relevant articles through December 2008 were reviewed by the task force and categorized by topic and level of evidence according to a modified schema used by the United States Preventative Services Task Force. Results: The revised guidelines for the management of thyroid nodules include recommendations regarding initial evaluation, clinical and ultrasound criteria for fine-needle aspiration biopsy, interpretation of fine-needle aspiration biopsy results, and management of benign thyroid nodules. Recommendations regarding the initial management of thyroid cancer include those relating to optimal surgical management, radioiodine remnant ablation, and suppression therapy using levothyroxine. Recommendations related to long-term management of differentiated thyroid cancer include those related to surveillance for recurrent disease using ultrasound and serum thyroglobulin as well as those related to management of recurrent and metastatic disease. Conclusions: We created evidence-based recommendations in response to our appointment as an independent task force by the American Thyroid Association to assist in the clinical management of patients with thyroid nodules and differentiated thyroid cancer. They represent, in our opinion, contemporary optimal care for patients with these disorders. © Copyright 2009, Mary Ann Liebert, Inc. |
Keywords: | treatment outcome; unclassified drug; thalidomide; clinical feature; clinical trial; review; cancer recurrence; sorafenib; doxorubicin; united states; bone metastasis; combined modality therapy; cancer staging; cancer diagnosis; lymph node dissection; lymph nodes; adenocarcinoma; metastasis; bortezomib; diagnosis, differential; tumor volume; clinical assessment; carcinoma, papillary; evidence based practice; practice guideline; diagnostic imaging; risk assessment; tumor suppressor gene; lung metastasis; radioactive iodine; iodine radioisotopes; disease progression; echography; biopsy, fine-needle; pazopanib; brain metastasis; gene therapy; long term care; medical society; glucocorticoid; recurrent disease; thyroidectomy; thyroid cancer; thyroid carcinoma; neck; thyroid neoplasms; cancer epidemiology; physical examination; axitinib; geldanomycin; levothyroxine; motesanib; thyroglobulin; aspiration biopsy; cervical lymph node; thyroglobulin blood level; thyroid nodule; thyroid gland |
Journal Title: | Thyroid |
Volume: | 19 |
Issue: | 11 |
ISSN: | 1050-7256 |
Publisher: | Mary Ann Liebert, Inc |
Date Published: | 2009-01-01 |
Start Page: | 1167 |
End Page: | 1214 |
Language: | English |
DOI: | 10.1089/thy.2009.0110 |
PUBMED: | 19860577 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | --- - "Cited By (since 1996): 161" - "Export Date: 30 November 2010" - "CODEN: THYRE" - "Source: Scopus" |