The treatment of well-differentiated thyroid cancer Journal Article
| Author: | Shaha, A. R. |
| Article Title: | The treatment of well-differentiated thyroid cancer |
| Abstract: | The management of well differentiated thyroid cancer continues to generate considerable debate and controversy regarding diagnostic evaluation, extent of surgery, and postoperative adjuvant therapy and follow-up. The fine-needle aspiration biopsy has been routinely used for diagnostic evaluation of thyroid nodule. Understanding prognostic factors and risk group analysis is extremely crucial in the overall management of thyroid cancer regarding the extent of thyroidectomy and adjuvant therapy. Patients in the low-risk group do extremely well and can be treated with lobectomy alone while those in the high-risk group invariably require total thyroidectomy due to the need of adjuvant radioactive iodine treatment. Thyroglobulin appears to be a good tumor marker in patients who have undergone total thyroidectomy during follow-up. One of the major nuances in the management of thyroid cancer is the availability of recombinant TSH which can be used for radioactive iodine dosimetry during the follow-up of patients with well differentiated thyroid cancer. This prevents patients from becoming hypothyroid for an extended period of time which directly affects their quality of life. Understanding poorly differentiated thyroid cancer is extremely crucial as an important histologic prognostic factor and generally being nonradioavid tumors. PET scan is useful in the follow-up of these patients to evaluate the extent of distant metastasis. |
| Keywords: | histopathology; cancer adjuvant therapy; cancer patient; cancer radiotherapy; postoperative care; nuclear magnetic resonance imaging; positron emission tomography; follow up; diagnostic procedure; metastasis; quality of life; computer assisted tomography; tumor differentiation; tumor marker; high risk patient; risk assessment; radioactive iodine; dosimetry; echography; thyroidectomy; thyroid cancer; hypothyroidism; thyroglobulin; aspiration biopsy; recombinant thyrotropin; thyroid surgery; thyroxine; thyroid scintiscanning; subtotal thyroidectomy; prognosis; human; article |
| Journal Title: | Operative Techniques in Otolaryngology - Head and Neck Surgery |
| Volume: | 14 |
| Issue: | 2 |
| ISSN: | 1043-1810 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2003-06-01 |
| Start Page: | 80 |
| End Page: | 85 |
| Language: | English |
| DOI: | 10.1016/s1043-1810(03)90004-2 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Export Date: 12 September 2014 -- Source: Scopus |
