Molecular body imaging: MR imaging, CT, and US. Part II. Applications Journal Article
| Authors: | Kircher, M. F.; Willmann, J. K. |
| Article Title: | Molecular body imaging: MR imaging, CT, and US. Part II. Applications |
| Abstract: | Molecular imaging is expected to have a major impact on the early diagnosis of diseases and disease monitoring in the next decade. Traditionally, nuclear imaging techniques have been the mainstay of molecular imaging in the clinical arena. However, with continued development of molecularly targeted contrast agents for nonnuclear imaging techniques such as magnetic resonance (MR), computed tomography (CT), and ultrasonography (US), the spectrum of clinical molecular imaging applications is expanding. In the second part of this review series, an overview of applications of molecular MR imaging-, CT-, and US-based imaging strategies that show promise for clinical translation is presented, and key challenges that need to be addressed to successfully translate these promising techniques in the future are discussed. © RSNA, 2012. |
| Keywords: | unclassified drug; review; bevacizumab; nonhuman; gemcitabine; pancreas cancer; cancer staging; nuclear magnetic resonance imaging; lymph node metastasis; metabolism; unindexed drug; computer assisted tomography; protein targeting; myeloperoxidase; vascular cell adhesion molecule 1; inflammation; molecular imaging; vasculotropin receptor 2; angiogenesis; skin carcinoma; colon cancer; atherosclerosis; echography; tumor cell; colitis; contrast medium; nanoparticle; tumor necrosis factor alpha inhibitor; folic acid; gadolinium pentetate; macrophage; tumor vascularization; vasculotropin antibody; ligand binding; integrin; streptavidin; liposome; ultrasmall superparamagnetic iron oxide; cell tracking; protamine sulfate; matrix metalloproteinase inhibitor; padgem protein; gadolinium chelate; phase 1 clinical trial (topic); oleic acid; carbon 13; ferucarbotran; ferumoxytol; superparamagnetic iron oxide; high density lipoprotein; lipoprotein; thrombogenesis; bismuth sulfate nanoparticle; fluorocarbon; polyaspartic acid |
| Journal Title: | Radiology |
| Volume: | 264 |
| Issue: | 2 |
| ISSN: | 0033-8419 |
| Publisher: | Radiological Society of North America, Inc. |
| Date Published: | 2012-08-01 |
| Start Page: | 349 |
| End Page: | 368 |
| Language: | English |
| DOI: | 10.1148/radiol.12111703 |
| PROVIDER: | scopus |
| PUBMED: | 22821695 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 4 September 2012" - "CODEN: RADLA" - "Source: Scopus" |
