Molecular imaging for personalized cancer care Journal Article
| Authors: | Kircher, M. F.; Hricak, H.; Larson, S. M. |
| Article Title: | Molecular imaging for personalized cancer care |
| Abstract: | Molecular imaging is rapidly gaining recognition as a tool with the capacity to improve every facet of cancer care. Molecular imaging in oncology can be defined as in vivo characterization and measurement of the key biomolecules and molecularly based events that are fundamental to the malignant state. This article outlines the basic principles of molecular imaging as applied in oncology with both established and emerging techniques. It provides examples of the advantages that current molecular imaging techniques offer for improving clinical cancer care as well as drug development. It also discusses the importance of molecular imaging for the emerging field of theranostics and offers a vision of how molecular imaging may one day be integrated with other diagnostic techniques to dramatically increase the efficiency and effectiveness of cancer care. © 2012 Federation of European Biochemical Societies. |
| Keywords: | cancer surgery; unclassified drug; review; bevacizumab; nonhuman; cancer radiotherapy; nuclear magnetic resonance imaging; cancer diagnosis; neoplasm staging; technetium 99m; neoplasms; imatinib; computer assisted tomography; molecular imaging; dasatinib; oncology; cetuximab; prostate cancer; patient care; echography; fluorodeoxyglucose f 18; computer assisted emission tomography; radiopharmaceutical agent; 1 fluoro 3 (2 nitro 1 imidazolyl) 2 propanol f 18; clinical effectiveness; abiraterone acetate; trastuzumab; single photon emission computer tomography; 3' fluorothymidine f 18; choline c 11; gallium 68; mri; antiestrogen; pet/ct; tirapazamine; personalized medicine; theranostics; androgen receptor antagonist; individualized medicine; optical imaging; diagnostics; 4 [3 [4 cyano 3 (trifluoromethyl)phenyl] 5,5 dimethyl 4 oxo 2 thioxo 1 imidazolidinyl] 2 fluoro n methylbenzamide; raman spectroscopy; hyperpolarized mri; mr spectroscopic imaging; mr/pet; pet/mri; fiacitabine; fluoro dihydrotestosterone f 18; fluoroazomycin arabinoside f 18; pyruvic acid c 13; thymidine f 18 |
| Journal Title: | Molecular Oncology |
| Volume: | 6 |
| Issue: | 2 |
| ISSN: | 1878-0261 |
| Publisher: | FEBS Press |
| Date Published: | 2012-04-01 |
| Start Page: | 182 |
| End Page: | 195 |
| Language: | English |
| DOI: | 10.1016/j.molonc.2012.02.005 |
| PROVIDER: | scopus |
| PUBMED: | 22469618 |
| PMCID: | PMC5528375 |
| DOI/URL: | |
| Notes: | Corrigendum issued, see DOI: 10.1016/j.molonc.2016.09.006 -- "Export Date: 4 June 2012" - "Source: Scopus" |
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