Real-time line-scanning reflectance confocal endoscope to enhance sectioning and reduce speckle for intraoral imaging Conference Paper

  


Authors: Glazowski, C.; Abeytunge, S.; Rajadhyaksha, M.
Title: Real-time line-scanning reflectance confocal endoscope to enhance sectioning and reduce speckle for intraoral imaging
Conference Title: Photonic Therapeutics and Diagnostics VIII
Abstract: The line-scanning confocal microscope is simpler than a point-scanning confocal microscope and allows for a smaller and lower cost footprint, making it attractive for endoscopic clinical use. The optical configuration affects image fidelity. Here, we present a benchtop version of an endoscopic line-scanning confocal microscope for intraoral imaging, with a divided pupil and optimal detection configuration (magnification, pixel-to-resolution ratio) to enhance image fidelity. Improved sectioning performance and reduction of "speckle" noise are demonstrated. A topology for use of a deformable MEMs mirror-based optical axial focus control for imaging in depth is presented. Preliminary images of human oral mucosa in vivo demonstrate feasibility for clinical application. © 2012 SPIE.
Keywords: confocal; microscopy; linescanning; microscopes; scanning; in-vivo; endoscopy; confocal microscopes; clinical application; fidelity; line-scanning; oral mucosa; microscopic examination; clinical use; speckle; turbid; mems; focus control; image fidelity; optical configurations; optimal detection
Journal Title Proceedings of SPIE
Volume: 8207
Conference Dates: 2012 Jan 21-24
Conference Location: San Francisco, CA
ISBN: 0277-786X
Publisher: SPIE  
Location: San Francisco, CA
Date Published: 2012-01-01
Start Page: 82071U
Language: English
DOI: 10.1117/12.908283
PROVIDER: scopus
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-84860726448&partnerID=40&md5=d287f9a95e577c3767353294493adb36
Notes: --- - Progress in Biomedical Optics and Imaging - Proceedings of SPIE - Progr. Biomed. Opt. Imaging Proc. SPIE - "Conference code: 89706" - "Export Date: 4 June 2012" - "Sponsors: The Society of Photo-Optical Instrumentation Engineers (SPIE)" - 21 January 2012 through 24 January 2012 - "Source: Scopus"
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MSK Authors
  1. Milind Rajadhyaksha
    223 Rajadhyaksha
  2. Christopher Edward Glazowski
    7 Glazowski
  3. Sanjeewa Abeytunge
    32 Abeytunge
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