Complications after radical cystectomy: Analysis of population-based data Journal Article


Authors: Konety, B. R.; Allareddy, V.; Herr, H.
Article Title: Complications after radical cystectomy: Analysis of population-based data
Abstract: Objectives: To determine the morbidity and mortality from radical cystectomy in a nationally representative population-derived sample. Complications after radical cystectomy have been reported from large single-institution series but population-based representative data are lacking. Methods: All patients undergoing radical cystectomy for bladder cancer were identified from the National Inpatient Sample data set of the Health Care Utilization Project (1998 to 2002). The prevalence of different complications coded according to the International Classification of Diseases, version 9, after cystectomy were determined. Independent hospital and patient-related factors associated with the occurrence of a complication were determined by logistic regression analysis. The prevalence of complication by type and frequency were compared with that in other large reported series. Results: The in-hospital mortality rate was 2.57%, and at least one complication other than death occurred in 28.4% of patients. These rates were comparable to those reported in published studies. Younger patients had a lower likelihood of complications. Younger patients and those undergoing cystectomy at large bed size, urban, teaching hospitals were less likely to have secondary complications after surgery, and younger patients, women, and those undergoing cystectomy at high-volume hospitals were less likely to have primary complications directly related to their surgery. Conclusions: The overall morbidity and mortality rates after radical cystectomy in a population-based sample were comparable to those reported from individual centers. Larger centers in urban locations may have lower complication rates but only hospitals performing a high volume of cystectomies were associated with fewer primary surgery-related complications. © 2006 Elsevier Inc. All rights reserved.
Keywords: adult; controlled study; aged; survival analysis; survival rate; major clinical study; diarrhea; united states; comparative study; disease association; heart disease; neuropathy; abdominal abscess; morbidity; prevalence; risk factors; kidney failure; bladder cancer; urinary bladder neoplasms; postoperative complication; postoperative complications; hospitals; health care utilization; health service; liver failure; blood transfusion reaction; death; heart failure; thromboembolism; cystectomy; hospital patient; postoperative infection; surgical mortality; multivariate analysis; sex difference; cardiopulmonary insufficiency; age distribution; intestine obstruction; hematoma; seroma; logistic regression analysis; wound infection; statistical model; wound dehiscence; wound complication; heart arrest; aspiration pneumonia; vascular disease; respiratory tract disease; phlebitis; urban population; international classification of diseases; puncture; rupture; hospital mortality; frequency analysis; functional disease; hepatorenal syndrome; septicemia; foreign body; hospital bed capacity; subphrenic abscess; septic shock; surgical wound; urinary dysfunction; oliguria; sample (statistics); thrombophlebitis; urinary tract disease; teaching hospital; digestive system disease; accidental injury; anuria; blood vessel rupture; hospital bed; kidney rupture; kidney tubule necrosis; laceration
Journal Title: Urology
Volume: 68
Issue: 1
ISSN: 0090-4295
Publisher: Elsevier Science, Inc.  
Date Published: 2006-07-01
Start Page: 58
End Page: 64
Language: English
DOI: 10.1016/j.urology.2006.01.051
PUBMED: 16806414
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 66" - "Export Date: 4 June 2012" - "CODEN: URGYA" - "Source: Scopus"
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  1. Harry W Herr
    594 Herr