Radical cystectomy in the octogenarian Journal Article


Authors: Stroumbakis, N.; Herr, H. W.; Cookson, M. S.; Fair, W. R.
Article Title: Radical cystectomy in the octogenarian
Abstract: Purpose: We evaluated the morbidity and outcome of cystectomy and urinary diversion in patients 80 years old or older with invasive bladder cancer. Materials and Methods: We reviewed the records of all patients older than 80 years who underwent cystectomy during the last 15 years. Of 1,186 cystectomies 44 patients (4%) were identified. Patients were evaluated for complications, mortality and functional status after surgery. Results: The 44 patients had a median age of 81 years (range 80 to 87). Of the patients 78% had significant co-morbidity, including 41% with 2 or mere medical problems. Median hospital stay was 14 days, with 20% of the patients requiring intensive care for 24 hours. There was a 51% complication rate including 25% due to surgical complications and 26% from underlying medical illness. Operative mortality was 4.5%. Within 6 months of surgery 66% were rehospitalized for medical or surgical reasons. Median survival time was 25 months. Median performance status before and after surgery decreased slightly from 70 to 65. Conclusions: The results of this study support the use of cystectomy in octogenarians with invasive bladder cancer. Surgery can be accomplished with acceptable morbidity and mortality. Radical cystectomy in this population offers the best opportunity for sustained disease-free quality survival.
Keywords: clinical article; controlled study; treatment outcome; aged; aged, 80 and over; survival rate; mortality; age factors; bladder cancer; urinary bladder neoplasms; intensive care; postoperative complication; postoperative complications; survival time; length of stay; feasibility studies; cystectomy; urinary diversion; comorbidity; surgical mortality; bladder neoplasms; humans; human; male; female; priority journal; article
Journal Title: Journal of Urology
Volume: 158
Issue: 6
ISSN: 0022-5347
Publisher: Elsevier Science, Inc.  
Date Published: 1997-12-01
Start Page: 2113
End Page: 2117
Language: English
DOI: 10.1016/s0022-5347(01)68171-0
PUBMED: 9366325
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 17 March 2017 -- Source: Scopus
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  1. Harry W Herr
    594 Herr
  2. William R Fair
    342 Fair
  3. Michael S. Cookson
    14 Cookson