Small cell lung cancer: Clinical Practice Guidelines in Oncology™ Journal Article
| Authors: | Johnson, B. E.; Crawford, J.; Downey, R. J.; Ettinger, D. S.; Fossella, F.; Grecula, J. C.; Jahan, T.; Kalemkerian, G. P.; Kessinger, A.; Koczywas, M.; Langer, C. J.; Martins, R.; Marymont, M. H.; Niell, H. B.; Ramnath, N.; Robert, F.; Williams, C. C. Jr |
| Article Title: | Small cell lung cancer: Clinical Practice Guidelines in Oncology™ |
| Abstract: | In 2005, approximately 26,000 new cases of small cell lung cancer were diagnosed in the United States. When compared with non-small cell lung cancer, SCLC generally has a more rapid doubling time, a higher growth fraction, and earlier development of widespread metastases. SCLC is highly sensitive to initial chemotherapy and radiotherapy. Treatment with chemotherapy plus chest radiotherapy can be curative for some patients with limited-stage SCLC, whereas most patients with extensive-stage disease who undergo chemotherapy alone experience palliated symptoms and prolonged survival. The updated 2006 NCCN guidelines include new principles of surgical resection as well as chemotherapy and radiation dosage changes. © Journal of the National Comprehensive Cancer Network. |
| Keywords: | cancer chemotherapy; cancer survival; cancer surgery; clinical feature; clinical trial; pathogenesis; review; cigarette smoking; salvage therapy; cisplatin; doxorubicin; area under the curve; cancer growth; drug dose reduction; drug potentiation; pathophysiology; gemcitabine; paclitaxel; cancer radiotherapy; chemotherapy; topotecan; cancer staging; cancer diagnosis; physician's practice patterns; cancer palliative therapy; heredity; carboplatin; bone marrow suppression; etoposide; blood toxicity; lung neoplasms; radiotherapy; granulocyte macrophage colony stimulating factor; nccn clinical practice guidelines; cyclophosphamide; vincristine; ifosfamide; docetaxel; irinotecan; febrile neutropenia; patient care; lung small cell cancer; systematic review; prophylaxis; carcinoma; medical oncology; platinum; targeted therapy; thorax radiography; surgical resection; taxane derivative; metastases; anthracycline derivative; navelbine; environmental factor; mediastinum; lobectomy; meta analysis; small cell; carcinoma, small cell; brain radiography; pulmonary carcinogenesis |
| Journal Title: | Journal of the National Comprehensive Cancer Network |
| Volume: | 4 |
| Issue: | 6 |
| ISSN: | 1540-1405 |
| Publisher: | Harborside Press |
| Date Published: | 2006-07-01 |
| Start Page: | 602 |
| End Page: | 622 |
| Language: | English |
| PUBMED: | 16813728 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 17" - "Export Date: 4 June 2012" - "Source: Scopus" |
