NCCN Clinical Practice Guidelines in Oncology: Small cell lung cancer Journal Article
| Authors: | Kalemkerian, G. P.; Akerley, W.; Downey, R. J.; Ettinger, D. S.; Fossella, F.; Grecula, J. C.; Jahan, T.; Johnson, B. E.; Kessinger, A.; Koczywas, M.; Langer, C. J.; Martins, R.; Niell, H. B.; Pan, C. C.; Ramnath, N.; Ready, N.; Robert, F.; Williams, C. C. Jr |
| Article Title: | NCCN Clinical Practice Guidelines in Oncology: Small cell lung cancer |
| Abstract: | Small cell lung cancer (SCLC) accounts for 15% of lung cancers. Nearly all cases of SCLC are attributable to cigarette smoking, and the remaining cases are presumably caused by environmental or genetic factors. Compared with non-small cell lung cancer, SCLC generally has a more rapid doubling time, a higher growth fraction, and earlier development of widespread metastases. SCLC is highly sensitive to initial chemotherapy and radiotherapy, but most patients eventually die from recurrent disease. These guidelines detail the management of SCLC from initial diagnosis and staging through treatment, and include information on supportive and palliative care. Important updates to the 2008 version include refined categories for performance status and the addition of topotecan as an option for patients who experience relapse. © Journal of the National Comprehensive Cancer Network 2008. |
| Keywords: | cancer survival; treatment response; clinical feature; review; salvage therapy; cisplatin; doxorubicin; united states; radiation dose; chemotherapy; cancer staging; heredity; carboplatin; etoposide; lung neoplasms; radiotherapy; smoking cessation; smoking; nccn clinical practice guidelines; cyclophosphamide; vincristine; irinotecan; lung small cell cancer; laboratory test; carcinoma; thorax radiography; surgical resection; elderly care; lobectomy; bone scintiscanning; small cell; carcinoma, small cell; pulmonary carcinogenesis |
| Journal Title: | Journal of the National Comprehensive Cancer Network |
| Volume: | 6 |
| Issue: | 3 |
| ISSN: | 1540-1405 |
| Publisher: | Harborside Press |
| Date Published: | 2008-01-01 |
| Start Page: | 294 |
| End Page: | 314 |
| Language: | English |
| PUBMED: | 18377848 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 4" - "Export Date: 2 July 2012" - "Source: Scopus" |
