Pulmonary neuroendocrine tumors: What (little) do we know? Journal Article


Authors: Chen, L. C.; Travis, W. D.; Krug, L. M.
Article Title: Pulmonary neuroendocrine tumors: What (little) do we know?
Abstract: Pulmonary neuroendocrine tumors are a distinct subset of tumors composing approximately 20% of all lung cancers. The major categories of pulmonary neuroendocrine tumors include typical and atypical carcinoids, large cell neuroendocrine carcinoma, and the more common small cell lung cancer. They are classified into different categories in the 2004 World Health Organization system, but share structural and morphologic features. Despite these shared features, their clinical characteristics range from indolent to aggressive, and therefore the approach to treatment depends on the histologic subtype. This article discusses the current understanding of the epidemiology, pathologic characteristics, treatment, and prognosis of this spectrum of diseases. © Journal of the National Comprehensive Cancer Network.
Keywords: cancer chemotherapy; cancer surgery; clinical feature; histopathology; review; cisplatin; doxorubicin; fluorouracil; alpha interferon; cancer radiotherapy; carboplatin; etoposide; lung neoplasms; lung cancer; cyclophosphamide; vincristine; morphology; docetaxel; irinotecan; neuroendocrine tumor; lung tumor; lung small cell cancer; carcinoid; world health organization; nomenclature; octreotide; cancer epidemiology; large cell carcinoma; cancer classification; navelbine; neuroendocrine tumors; small cell lung cancer; streptozocin
Journal Title: Journal of the National Comprehensive Cancer Network
Volume: 4
Issue: 6
ISSN: 1540-1405
Publisher: Harborside Press  
Date Published: 2006-07-01
Start Page: 623
End Page: 630
Language: English
PUBMED: 16813729
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 9" - "Export Date: 4 June 2012" - "Source: Scopus"
Citation Impact
MSK Authors
  1. Lin-Chi Chen
    13 Chen
  2. Lee M Krug
    178 Krug
  3. William D Travis
    743 Travis