Melanoma of the lentigo maligna subtype: Diagnostic challenges and current treatment paradigms Journal Article
| Authors: | McGuire, L. K.; Disa, J. J.; Lee, E. H.; Busam, K. J.; Nehal, K. S. |
| Article Title: | Melanoma of the lentigo maligna subtype: Diagnostic challenges and current treatment paradigms |
| Abstract: | Melanoma of the lentigo maligna subtype presents diagnostic and treatment challenges because of ill-defined clinical margins in cosmetically and functionally sensitive areas of the head and neck with extensive sun damage. This review highlights the natural history, varied clinical presentations, and pitfalls in histologic diagnosis. The focus is on the surgical management, comparing excision and pathologic tissue processing techniques of wide excision, Mohs micrographic surgery, and staged excision. Staged excision is recommended for optimal surgical margin control. Nonsurgical treatment modalities are also reviewed for the elderly or unresectable cases. Copyright © 2012 by the American Society of Plastic Surgeons. |
| Journal Title: | Plastic and Reconstructive Surgery |
| Volume: | 129 |
| Issue: | 2 |
| ISSN: | 0032-1052 |
| Publisher: | Lippincott Williams & Wilkins |
| Date Published: | 2012-02-01 |
| Start Page: | 288e |
| End Page: | 299e |
| Language: | English |
| DOI: | 10.1097/PRS.0b013e31823aeb72 |
| PROVIDER: | scopus |
| PUBMED: | 22286443 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 1 March 2012" - "CODEN: PRSUA" - "Source: Scopus" |
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