Histologic processing and evaluation of surgical excision specimens Book Section
| Authors: | Giordano, C. N.; Connolly, K. L.; Busam, K. J.; Nehal, K. S. |
| Editors: | Nehal, K. S.; Busam, K. J. |
| Article/Chapter Title: | Histologic processing and evaluation of surgical excision specimens |
| Abstract: | Lentigo maligna (LM) and lentigo maligna melanoma (LMM) are often characterized by extensive subclinical extension, complicating the surgical treatment of this melanoma subtype. Standard surgical margins have proven ineffective in achieving adequate clearance, and margin-controlled surgical techniques such as staged excision and Mohs micrographic surgery have largely replaced standard excision as the gold standard for care. Each of these margin-controlled methods has variations in the surgical technique and histologic processing of the excision specimen but the common goal is to examine surgical margins in a meticulous manner prior to reconstruction. It is imperative that the surgeon has a thorough understanding of the varied histologic processing methods available, along with the advantages, limitations, and potential pitfalls of each, in order to optimize tumor clearance and long term cure rates. © Springer International Publishing Switzerland 2017. |
| Keywords: | staging; lentigo maligna; frozen sections; staged excision; lentigo maligna melanoma; rush permanent sections; breadloaf; en face; radial sectioning; unsuspected invasion |
| Book Title: | Lentigo Maligna Melanoma: Challenges in Diagnosis and Management |
| ISBN: | 978-3-319-43785-9 |
| Publisher: | Springer |
| Publication Place: | Cham, Switzerland |
| Date Published: | 2017-01-01 |
| Start Page: | 89 |
| End Page: | 111 |
| Language: | English |
| DOI: | 10.1007/978-3-319-43787-3_8 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Book Chapter: 8 -- Export Date: 2 June 2017 -- Source: Scopus |
Altmetric
Citation Impact
BMJ Impact Analytics
Related MSK Work