Role of tracheal resection in thyroid cancer Journal Article

  


Authors: Chernichenko, N.; Shaha, A. R.
Article Title: Role of tracheal resection in thyroid cancer
Abstract: To provide a critical review of recent literature on the role of tracheal resection in thyroid cancer. The current body of literature is centered on the controversy regarding how radical the extent of tracheal resection needs to be to achieve long-term control of thyroid carcinoma with tracheal invasion. Proponents of shave excision are guided by the reported survival outcomes comparable to segmental resections in a selected group of patients. Others believe that all patients should have a segmental sleeve resection to ensure clearance of transmural disease. Recent advances in microsurgical reconstruction may allow selected patients to undergo tracheal resection when a large tracheal defect is anticipated. Tracheal invasion by well differentiated carcinoma is a marker of a more aggressive tumor behavior, defining a subpopulation of patients at a greater risk of recurrence and death. The goal of surgical intervention in this scenario is complete resection with no gross residual disease. A well designed prospective multi-institutional trial, taking into account depth of invasion, risk group stratification, histology, presence of distant metastasis, radioactive iodine trapping ability, adjuvant treatment, and long-term survival data, is needed to compare the outcomes following more conservative shave excision and segmental tracheal resection.
Keywords: review; cancer staging; methodology; neoplasm staging; pathology; cancer invasion; neoplasm invasiveness; thyroid neoplasms; thyroid tumor; tracheotomy
Journal Title: Current Opinion in Oncology
Volume: 24
Issue: 1
ISSN: 1040-8746
Publisher: Lippincott Williams & Wilkins  
Date Published: 2012-01-01
Start Page: 29
End Page: 34
Language: English
PUBMED: 22048058
PROVIDER: scopus
DOI: 10.1097/CCO.0b013e32834d6dd7
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85027928611&partnerID=40&md5=0713a2098175becf016dba8e2aaee8c8
Notes: --- - "Export Date: 1 March 2012" - "Source: Scopus"
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MSK Authors
  1. Ashok R Shaha
    697 Shaha
  2. Natalya Chernichenko
    21 Chernichenko
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