Does minimally invasive surgery for radical cystectomy provide similar long-term cancer control as open radical surgery? Journal Article

  

Authors:	Keren-Paz, G. E.; Laudone, V. P.; Bochner, B. H.
Article Title:	Does minimally invasive surgery for radical cystectomy provide similar long-term cancer control as open radical surgery?
Abstract:	PURPOSE OF REVIEW: Open radical cystectomy (ORC) and pelvic lymph node dissection (PLND) is the standard treatment for muscle-invasive and high-risk nonmuscle-invasive bladder cancer (BCa), but is associated with significant morbidity. In the hope of decreasing the complications and improving the surgical tolerance, minimally invasive techniques to perform radical cystectomy and PLND have been adopted. This review focuses on the present state of the literature regarding the oncological efficacy of minimally invasive radical cystectomy (MIRC) and PLND. RECENT FINDINGS: Most studies are retrospective, single surgeon or institution, and are subjected to significant selection bias. There is scarce data regarding intermediate and long term oncological outcomes following MIRC, and most reported series contain a lower proportion of patients with locally advanced disease compared with ORC series. Positive surgical margin rates are similar between the approaches in localized disease, but may be significantly higher in MIRC in patients with more advanced tumors. SUMMARY: The current review of the literature demonstrates insufficient evidence regarding the long-term oncological outcomes of MIRC. There is a need for well controlled, prospective, randomized trials with sufficient follow-up to compare MIRC to ORC for the treatment of invasive BCa before the oncologic efficacy of these techniques can be adequately compared to the standards established by ORC. © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins.
Keywords:	bladder cancer; oncological outcomes; minimally invasive radical cystectomy
Journal Title:	Current Opinion in Urology
Volume:	23
Issue:	5
ISSN:	0963-0643
Publisher:	Lippincott Williams & Wilkins
Date Published:	2013-09-01
Start Page:	449
End Page:	455
Language:	English
DOI:	10.1097/MOU.0b013e328363a8a7
PROVIDER:	scopus
PUBMED:	23880741
DOI/URL:	http://www.scopus.com/inward/record.url?eid=2-s2.0-84881664137&partnerID=40&md5=35c6080ff6f13cf5b18323263ab25e38
Notes:	--- - "Export Date: 4 September 2013" - "CODEN: CUOUE" - "Source: Scopus"

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