Respiratory syncytial virus and human metapneumovirus Book Section

  


Authors: Esther Babady, N.; Tang, Y. W.
Editors: Landry, M. L.; Richter, S. S.; Warnock, D. W.
Article/Chapter Title: Respiratory syncytial virus and human metapneumovirus
Abstract: Respiratory syncytial virus (RSV) and human metapneumovirus (HMPV) are recognized as the most serious causes of severe acute lower respiratory tract illnesses in young children and infants. Rapid and accurate detection and characterization of RSV is important in the clinical management of individual patients because of the availability of specific antiviral drugs. Early detection of RSV and HMPV infections is also necessary for cohorting of infected patients to prevent nosocomial spread. Tube and shell viral cultures remain the gold standard for RSV and HMPV detection, but they are time consuming and require attention to transport and prompt inoculation. Quite a few of rapid viral antigen tests are commercially available, which yield results within 1 hour after specimen collection. However, their sensitivity is limited and negative results usually require a more sensitive back-up test such as a molecular assay or culture. With the increased number of multiplexed molecular Food and Drug Administration (FDA)-approved assays, simultaneous detection and identification of common viral pathogens is becoming the main tool for detection and identification of RSV and MPHV. © 2015 by ASM Press.
Keywords: ribavirin; respiratory syncytial virus; human metapneumovirus; avian pneumoviruses; polyclonal human immunoglobulin
Book Title: Manual of Clinical Microbiology. 11th edition
ISBN: 978-168367280-7
Publisher: Wiley Blackwell  
Publication Place: Washington, DC
Date Published: 2015-01-01
Start Page: 1498
End Page: 1518
Language: English
DOI: 10.1128/9781555817381.ch86
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-105000671406&doi=10.1128%2f9781555817381.ch86&partnerID=40&md5=4a9b00c3b24281c2dade67b06901d808
Notes: Book chapter: 86 -- Source: Scopus
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MSK Authors
  1. Ngolela Esther Babady
    170 Babady
  2. Yi-Wei Tang
    188 Tang
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