Mastering rectal cancer MRI: From foundational concepts to optimal staging Review


Authors: Modena Heming, C. A.; Alvarez, J. A.; Miranda, J.; Cardoso, D.; Almeida Ghezzi, C. L.; Nogueira, G. F.; Costa-Silva, L.; Damasceno, R. S.; Morita, T. O.; Smith, J. J.; Horvat, N.
Review Title: Mastering rectal cancer MRI: From foundational concepts to optimal staging
Abstract: MRI plays a critical role in the local staging, restaging, surveillance, and risk stratification of patients, ensuring they receive the most tailored therapy. As such, radiologists must be familiar not only with the key MRI findings that influence management decisions but also with the appropriate MRI protocols and structured reporting. Given the complexity of selecting the optimal therapy for each patient—which often requires multidisciplinary discussions—radiologists should be well-versed in relevant treatment strategies and surgical terms, understanding their significance in guiding patient care. In this manuscript, we review the most common treatment options for managing patients with rectal adenocarcinoma, emphasizing key MRI principles and protocol characteristics for accurate staging. We also highlight important anatomical landmarks and essential factors to be described during baseline assessment. Additionally, we discuss crucial information for restaging and surveillance. © 2025 Elsevier B.V.
Keywords: review; neoadjuvant therapy; cancer staging; nuclear magnetic resonance imaging; magnetic resonance imaging; neoplasm staging; radiologist; diagnosis; surgery; rectal neoplasms; rectum cancer; rectum tumor; rectal cancer; protocol; rectal adenocarcinoma; human; mri scanner; anatomical landmark
Journal Title: European Journal of Radiology
Volume: 183
ISSN: 0720-048X
Publisher: Elsevier B.V  
Date Published: 2025-02-01
Start Page: 111937
Language: English
DOI: 10.1016/j.ejrad.2025.111937
PROVIDER: scopus
PUBMED: 39864243
DOI/URL:
Notes: Review -- Source: Scopus
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