Restaging magnetic resonance imaging of the rectum after neoadjuvant therapy: A practical guide Review


Authors: Horvat, N.; Miranda, J.; Kinochita, F.; de Carvalho, T. L.; Torri, G. B.; Lopes, T. J. P.; Nomura, C. H.
Review Title: Restaging magnetic resonance imaging of the rectum after neoadjuvant therapy: A practical guide
Abstract: Colorectal cancer is the third most common cancer and the second leading cause of cancer-related death. Rectal cancer accounts for approximately one-third of new colorectal cancer cases, with adenocarcinoma as the predominant subtype. Despite an overall decline in colorectal cancer incidence and mortality, due to advancements in screening, early diagnosis, and treatment options, there is a concerning increase in incidence rates among young patients. Recent significant advances in managing locally advanced rectal cancer, such as the establishment of different surgical approaches, neoadjuvant treatment using different protocols for high-risk cases, and the adoption of organ-preservation strategies, have increased the importance of the role played by radiologists in locoregional assessment on magnetic resonance imaging at baseline, at restaging, and during active surveillance of patients with rectal cancer. In this article, we review the role of restaging rectal magnetic resonance imaging after neoadjuvant therapy, providing radiologists with a practical, step-by-step guide for assessing treatment response. © Colégio Brasileiro de Radiologia e Diagnóstico por Imagem.
Keywords: treatment outcome; treatment response; review; neoadjuvant therapy; nuclear magnetic resonance imaging; magnetic resonance imaging; cancer incidence; colorectal cancer; radiotherapy; radiologist; active surveillance; organ preservation; drug therapy; rectal neoplasms; rectum cancer; rectum tumor; therapy; rectum; human; male
Journal Title: Radiologia Brasileira
Volume: 57
ISSN: 0100-3984
Publisher: Colegio Brasileiro de Radiologia * Departamento da Associacao Medica Brasileira  
Date Published: 2024-01-01
Start Page: e20240004
Language: English
DOI: 10.1590/0100-3984.2024.0004
PROVIDER: scopus
PMCID: PMC11268099
PUBMED: 39050261
DOI/URL:
Notes: The MSK Cancer Center Support Grant (P30 CA008748) is acknowledge in the PDF -- Corresponding authors is MSK author: Natally Horvat -- Source: Scopus
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  1. Natally Horvat
    101 Horvat