| Abstract: |
This review examines nanomedicine's dynamic landscape, emphasizing vanadium oxide nanoparticles (V2O5 NPs) and their pivotal role in antimicrobial and anticancer therapies. It elucidates V2O5 NPs' mechanisms, revealing their disruption of redox homeostasis, mitochondrial function, and potent anti-angiogenic effects. Highlighting significant findings, the research emphasizes V2O5 NPs' robust anticancer efficacy through apoptosis and ferroptosis induction in tumor cells. V2O5 NPs demonstrate versatile antioxidant properties and compelling anti-colorectal cancer effects. The nuanced interplay between V2O5 NP size and cytotoxicity underscores the importance of tailoring nanoparticle characteristics for enhanced therapeutic effectiveness. Despite promising results, translating V2O5 NPs to clinical practice faces challenges like safety concerns, optimizing therapeutic efficacy, and regulatory complexities. Collaborative efforts among the scientific community, industry partners, and regulatory bodies are crucial for advancing V2O5 NPs in antimicrobial and anticancer therapies. Collective commitment is vital for unlocking V2O5 NPs' full potential and revolutionizing medical applications. This collaborative endeavour promises innovative and effective therapeutic interventions, reshaping nanomedicine's landscape. © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024. |
