Non-emergent hemoptysis in patients with primary or metastatic lung tumors: The role of transarterial embolization Journal Article
| Authors: | Geevarghese, R.; Petre, E.; Ziv, E.; Santos, E.; Rodriguez, L.; Zhao, K.; Sotirchos, V. S.; Solomon, S. B.; Alexander, E. S. |
| Article Title: | Non-emergent hemoptysis in patients with primary or metastatic lung tumors: The role of transarterial embolization |
| Abstract: | Purpose: To evaluate the role of systemic arterial embolization for the management of non-emergent hemoptysis in patients with primary or metastatic lung tumors. Materials and methods: This is a retrospective single center study of consecutive patients who underwent systemic arterial embolization for non-emergent hemoptysis between 2011 and 2023. Study endpoints included technical success, clinical success (partial or complete resolution of hemoptysis) and overall survival. Hemoptysis-free and overall survival were estimated using the Kaplan-Meier method. Predictive factors for hemoptysis-free survival and overall survival were evaluated using univariate analysis (Cox regression). Post-procedural 30-day adverse events were recorded in line with Common Terminology Criteria for Adverse Events (CTCAE) v5.0. Results: A total of 30 patients were identified. Technical success was achieved in 24/30 (80 %) patients. Clinical success following embolization was achieved in 23/30 (76.7 %) patients. Median length of hospitalization was 5 days (Range: 1 to 16 days). Median overall survival was 194 days (95 % CI: 89 to 258). Median hemoptysis-free survival was 286 days (95 % CI: 42 to not reached). No significant clinical or procedural predictors of hemoptysis-free survival or overall survival were identified. Serious adverse events (CTCAE Grade > 3) occurred in 1 patient (3.4 % − fatal respiratory failure). Conclusion: Embolization of non-emergent hemoptysis in patients with lung malignancies is safe and effective. Recurrence is however high in this patient population, likely due to the nature of the underlying disease. © 2024 Elsevier B.V. |
| Keywords: | adult; clinical article; controlled study; aged; overall survival; mortality; chemoembolization; computer assisted tomography; anemia; nausea; vomiting; delirium; cohort analysis; lung cancer; creatinine; hemoglobin; retrospective study; abdominal pain; length of stay; lung metastasis; limb swelling; bronchoscopy; antithrombocytic agent; anticoagulant agent; sore throat; hemoptysis; embolization; clinical outcome; bronchodilating agent; cannulation; hypercapnia; arterial embolization; human; male; female; article; transarterial embolization; non-emergent |
| Journal Title: | European Journal of Radiology |
| Volume: | 181 |
| ISSN: | 0720-048X |
| Publisher: | Elsevier B.V |
| Date Published: | 2024-12-01 |
| Start Page: | 111786 |
| Language: | English |
| DOI: | 10.1016/j.ejrad.2024.111786 |
| PROVIDER: | scopus |
| PUBMED: | 39423778 |
| PMCID: | PMC12103911 |
| DOI/URL: | |
| Notes: | Article -- Source: Scopus |
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