Reprogrammed Schwann cells in cancer Book Section

  


Authors: Deborde, S.; Wong, R. J.
Editors: Amit, M.; Scheff, N. N.
Article/Chapter Title: Reprogrammed Schwann cells in cancer
Abstract: Nerves and their most abundant cell type, Schwann cells (SCs), are novel and important players in the tumor microenvironment. SCs constitute a family of cell subtypes with a variety of functions associated with neuronal functions. SCs facilitate the transmission of neural impulses, provide nutrients to neurons, protect neurons, guide axons in nerve repair, and regulate immune functions. In cancer, recent studies have revealed a reprogramming of SCs accompanied by an active role in promoting cancer cell invasion. These reprogrammed SCs form tracks that allow cancer invasion. The clinical significance of SC activation by cancer has recently been shown in pancreatic ductal adenocarcinoma. © Springer Nature Switzerland AG 2023. All rights reserved.
Keywords: communication; reprogramming; schwann cells; nerves; cancer
Book Title: Cancer Neuroscience
ISBN: 978-3-031-32428-4
Publisher: Springer  
Publication Place: Cham, Switzerland
Date Published: 2023-01-01
Start Page: 131
End Page: 144
Language: English
DOI: 10.1007/978-3-031-32429-1_9
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85199732818&doi=10.1007%2f978-3-031-32429-1_9&partnerID=40&md5=b62aac8529ec7ff8fafe25285ca17e1c
Notes: Book chapter: 9 -- Source: Scopus
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MSK Authors
  1. Richard J Wong
    412 Wong
  2. Sylvie Deborde
    20 Deborde
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