The role of Schwann cells in cancer Review


Authors: Deborde, S.; Wong, R. J.
Review Title: The role of Schwann cells in cancer
Abstract: Schwann cells (SCs) are the most abundant cell type in the nerves in the peripheral nervous system and compose a family of subtypes that are endowed with a variety of different functions. SCs facilitate the transmission of neural impulses, provide nutrients and protection for neurons, guide axons in nerve repair, and regulate immune functions. In the context of cancer, recent studies have revealed an active role of SCs in promoting cancer cell invasion, modulating immune responses, and transmitting pain sensation. © 2022 Wiley-VCH GmbH.
Keywords: neoplasm; neoplasms; cytology; metabolism; neurons; physiology; cell types; schwann cell; nerve regeneration; axons; diseases; cancer cells; repair; peripheral nervous system; reprogramming; cells; schwann cells; axon; immune function; cancer; nerve repair; cell-be; cell/b.e; cell/be
Journal Title: Advanced Biology
Volume: 6
Issue: 9
ISSN: 2701-0198
Publisher: Wiley Vch Gmbh  
Date Published: 2022-09-01
Start Page: 2200089
Language: English
DOI: 10.1002/adbi.202200089
PUBMED: 35666078
PROVIDER: scopus
PMCID: PMC9474572
DOI/URL:
Notes: Review -- Export Date: 3 October 2022 -- Source: Scopus
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  1. Richard J Wong
    412 Wong
  2. Sylvie Deborde
    20 Deborde