Features of benign epidermal nonmelanocytic lesions on ex vivo confocal microscopy and histopathologic correlation Book Section
| Authors: | Farabi, B.; Harris, U.; Jain, M.; Hartmann, D.; Rao, B. K. |
| Editors: | Jain, M.; Rossi, A.; Nehal, K.; Sendín-Martín, M. |
| Article/Chapter Title: | Features of benign epidermal nonmelanocytic lesions on ex vivo confocal microscopy and histopathologic correlation |
| Abstract: | External stimuli such as ultraviolet radiation (UVR) or viruses can cause benign or malignant skin lesions. Solar lentigo (SL) and seborrheic keratosis (SK) are benign nonmelanocytic epidermal lesions that are commonly seen on sun-damaged skin of patients undergoing Mohs surgery; thus, it is crucial to identify them on frozen sections or freshly excised tissues and differentiate them from skin cancers such as basal cell carcinoma (BCCC), squamous cell carcinoma (SCC), and melanoma. Verruca vulgaris (VV) and molluscum contagiosum (MC) are viral-induced epidermal skin lesions, which are commonly seen in all age groups and can mimic other benign or malignant solitary lesions of the skin. EVCM may rapidly evaluate these lesions and differentiate them from their malignant counterpart. Although EVCM features MC [1] and Herpes simplex virus [2] have been described before, features of VV, SL, and SK have never been described in the literature. In this chapter, we will first provide a brief introduction to clinical and pathologic features of SL, SK, VV, and MC and then define morphological features of these lesions on EVCM (fluorescence and digital H&E modes) and compare them with their histopathological findings. © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022. |
| Keywords: | seborrheic keratosis; verruca vulgaris; molluscum contagiosum; solar lentigo; histopathologic correlation; fluorescence confocal microscopy; ex vivo confocal microscopy; digital he |
| Book Title: | Cutaneous Atlas of Ex Vivo Confocal Microscopy |
| ISBN: | 978-3-030-89315-6 |
| Publisher: | Springer Nature |
| Publication Place: | Cham, Switzerland |
| Date Published: | 2022-01-01 |
| Start Page: | 53 |
| End Page: | 66 |
| Language: | English |
| DOI: | 10.1007/978-3-030-89316-3_5 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Book Chapter: 5 -- Located in "Part III: Benign Skin Tumours" -- Source: Scopus |
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