An update on selected cutaneous (myo) fibroblastic mesenchymal tumors Review
| Authors: | Georgantzoglou, N.; Linos, K. |
| Review Title: | An update on selected cutaneous (myo) fibroblastic mesenchymal tumors |
| Abstract: | Cutaneous (myo)fibroblastic tumors constitute a group of tumors with overlapping clinicopathological features and variable biologic behavior. In the present review we focus on the histomorphology, immunohistochemical profile and molecular background of the following entities: dermatofibrosarcoma protuberans (DFSP), CD34-positive fibroblastic tumor (SCD34FT), myxoinflammatory sarcoma (MIFS), low-grade myofibroblastic sarcoma, solitary fibrous tumor and nodular fasciitis. Although some of these entities typically arise in deep-seated locations, they may occasionally present as cutaneous/superficial tumors and might be challenging to recognize. This review covers in depth the latest advances in molecular diagnostics and immunohistochemical markers that have significantly facilitated the correct classification and diagnosis of these neoplasms. © 2023 |
| Keywords: | immunohistochemistry; review; cd34 antigen; skin neoplasms; diagnosis, differential; differential diagnosis; pathology; tumor marker; sarcoma; patient care; skin tumor; fibrosarcoma; cancer classification; solitary fibrous tumor; soft tissue neoplasms; soft tissue tumor; dermatofibrosarcoma; dermatofibrosarcoma protuberans; myxoinflammatory fibroblastic sarcoma; myofibroblastic sarcoma; fasciitis; humans; human; nodular fasciitis; biomarkers, tumor; low-grade myofibroblastic sarcoma; superficial cd34 fibroblastic tumor; cutaneous myofibroblastic mesenchymal tumor |
| Journal Title: | Seminars in Diagnostic Pathology |
| Volume: | 40 |
| Issue: | 4 |
| ISSN: | 0740-2570 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2023-07-01 |
| Start Page: | 295 |
| End Page: | 305 |
| Language: | English |
| DOI: | 10.1053/j.semdp.2023.04.018 |
| PUBMED: | 37150655 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Source: Scopus |
