Clinical utility of (18)F-2-fluoro-deoxy-d-glucose PET imaging in locally advanced esophageal/gastroesophageal junction adenocarcinoma Review


Authors: Cowzer, D.; Keane, F.; Ku, G. Y.
Review Title: Clinical utility of (18)F-2-fluoro-deoxy-d-glucose PET imaging in locally advanced esophageal/gastroesophageal junction adenocarcinoma
Abstract: Esophageal adenocarcinoma, including adenocarcinoma of the gastroesophageal junction, is uncommon in the United States, but is associated with a rising incidence in young adults, and has a traditionally poor prognosis. Despite the incremental benefits that have been made with multimodality approaches to locally advanced disease, most patients will go on to develop metastatic disease, and long-term outcomes remain suboptimal. Over the last decade, PET-CT has emerged as a key tool in the management of this disease, with several prospective and retrospective studies evaluating its role in this disease. Herein, we review the key data pertaining to the use of PET-CT in the management of locally advanced esophageal and GEJ adenocarcinoma, with a focus on staging, prognostication, PET-CT adapted therapy in the neoadjuvant setting, and surveillance. © 2023 by the authors.
Keywords: staging; adenocarcinoma; preoperative treatment; esophageal cancer; pet/ct; suv
Journal Title: Diagnostics
Volume: 13
Issue: 11
ISSN: 2075-4418
Publisher: MDPI  
Date Published: 2023-06-01
Start Page: 1884
Language: English
DOI: 10.3390/diagnostics13111884
PROVIDER: scopus
PMCID: PMC10252409
PUBMED: 37296735
DOI/URL:
Notes: Review -- Source: Scopus
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  1. Geoffrey Yuyat Ku
    230 Ku
  2. Darren Cowzer
    29 Cowzer
  3. Fergus Keane
    30 Keane