(18)F-FDG PET/CT for image-guided and intensity-modulated radiotherapy Journal Article


Authors: Ford, E. C.; Herman, J.; Yorke, E.; Wahl, R. L.
Article Title: (18)F-FDG PET/CT for image-guided and intensity-modulated radiotherapy
Abstract: Advances in technology have allowed extremely precise control of radiation dose delivery and localization within a patient. The ability to confidently delineate target tumor boundaries, however, has lagged behind. (18)F-FDG PET/CT, with its ability to distinguish metabolically active disease from normal tissue, may provide a partial solution to this problem. Here we review the current applications of (18)F-FDG PET/CT in a variety of disease sites, including non-small cell lung cancer, head and neck cancer, and pancreatic adenocarcinoma. This review focuses on the use of (18)F-FDG PET/CT to aid in planning radiotherapy and the associated benefits and challenges. We also briefly consider novel radiopharmaceuticals that are beginning to be used in the context of radiotherapy planning. Copyright © 2009 by the Society of Nuclear Medicine, Inc.
Keywords: review; intensity modulated radiation therapy; nonhuman; treatment planning; lung non small cell cancer; head and neck cancer; imrt; fluorodeoxyglucose f 18; computer assisted emission tomography; pancreas adenocarcinoma; radiation therapy; fdg (fluorodeoxyglucose); fdg pet/ct; igrt
Journal Title: Journal of Nuclear Medicine
Volume: 50
Issue: 10
ISSN: 0161-5505
Publisher: Society of Nuclear Medicine  
Date Published: 2009-10-01
Start Page: 1655
End Page: 1665
Language: English
DOI: 10.2967/jnumed.108.055780
PROVIDER: scopus
PMCID: PMC2899678
PUBMED: 19759099
DOI/URL:
Notes: --- - "Cited By (since 1996): 11" - "Export Date: 30 November 2010" - "CODEN: JNMEA" - "Source: Scopus"
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
  1. Ellen D Yorke
    450 Yorke
Related MSK Work