Authors: | Ford, E. C.; Herman, J.; Yorke, E.; Wahl, R. L. |
Article Title: | (18)F-FDG PET/CT for image-guided and intensity-modulated radiotherapy |
Abstract: | Advances in technology have allowed extremely precise control of radiation dose delivery and localization within a patient. The ability to confidently delineate target tumor boundaries, however, has lagged behind. (18)F-FDG PET/CT, with its ability to distinguish metabolically active disease from normal tissue, may provide a partial solution to this problem. Here we review the current applications of (18)F-FDG PET/CT in a variety of disease sites, including non-small cell lung cancer, head and neck cancer, and pancreatic adenocarcinoma. This review focuses on the use of (18)F-FDG PET/CT to aid in planning radiotherapy and the associated benefits and challenges. We also briefly consider novel radiopharmaceuticals that are beginning to be used in the context of radiotherapy planning. Copyright © 2009 by the Society of Nuclear Medicine, Inc. |
Keywords: | review; intensity modulated radiation therapy; nonhuman; treatment planning; lung non small cell cancer; head and neck cancer; imrt; fluorodeoxyglucose f 18; computer assisted emission tomography; pancreas adenocarcinoma; radiation therapy; fdg (fluorodeoxyglucose); fdg pet/ct; igrt |
Journal Title: | Journal of Nuclear Medicine |
Volume: | 50 |
Issue: | 10 |
ISSN: | 0161-5505 |
Publisher: | Society of Nuclear Medicine |
Date Published: | 2009-10-01 |
Start Page: | 1655 |
End Page: | 1665 |
Language: | English |
DOI: | 10.2967/jnumed.108.055780 |
PROVIDER: | scopus |
PMCID: | PMC2899678 |
PUBMED: | 19759099 |
DOI/URL: | |
Notes: | --- - "Cited By (since 1996): 11" - "Export Date: 30 November 2010" - "CODEN: JNMEA" - "Source: Scopus" |