Clinical utility of (18)F-FDG PET/CT for staging and treatment planning in urachal adenocarcinoma Journal Article


Authors: Das, J. P.; Vargas, H. A.; Ghafoor, S.; Goh, A. C.; Ulaner, G. A.
Article Title: Clinical utility of (18)F-FDG PET/CT for staging and treatment planning in urachal adenocarcinoma
Abstract: Our objective was to evaluate the impact of F-18-FDG PET CT on the management of urachal adenocarcinoma (UrC-ADC). Methods: A retrospective analysis of patients with UrC-ADC from 2001 to 2019 at Memorial Sloan Kettering was performed. Mayo stage before F-18-FDG PET/CT, rate of detection of the primary malignancy and metastases on F-18-FDG PET/CT, Mayo stage after F-18-FDG PET/CT, and change in patient management were determined. Results: Of 21 patients with UrC-ADC before F-18-FDG PET/CT, Mayo staging was I/II in 8, III in 3, and IV in 10. F-18-FDG PET/CT detected previously unidentified metastases in 8 (38%) of 21 patients, resulting in upstaging of disease in 3 (14%) patients and a change in treatment in 4 (19%) patients. Conclusion: F-18-FDG PET/CT has clinical utility in patients with UrC-ADC by identifying metastatic disease not appreciated on anatomic imaging, leading to changes in staging and patient management.
Keywords: survival; staging; carcinoma; urachus; f-18-fdg pet/ct; cancer; urachal adenocarcinoma
Journal Title: Journal of Nuclear Medicine
Volume: 62
Issue: 5
ISSN: 0161-5505
Publisher: Society of Nuclear Medicine  
Date Published: 2021-05-10
Start Page: 643
End Page: 647
Language: English
ACCESSION: WOS:000755623900020
DOI: 10.2967/jnumed.120.251561
PROVIDER: wos
PMCID: PMC8844264
PUBMED: 32948680
Notes: Article -- Source: Wos
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
  1. Gary Ulaner
    146 Ulaner
  2. Alvin Chun chin Goh
    72 Goh
  3. Soleen Ghafoor
    17 Ghafoor
  4. Jeeban Paul Das
    41 Das