Role of positron emission tomography in urological oncology Journal Article


Authors: Rioja, J.; Rodríguez-Fraile, M.; Lima-Favaretto, R. ; Rincón-Mayans, A.; Peñuelas-Sánchez, I.; Zudaire-Bergera, J. J.; Parra, R. O.
Article Title: Role of positron emission tomography in urological oncology
Abstract: • Positron emission tomography (PET) is a diagnostic tool using radiotracers to show changes in metabolic activities in tissues. We analysed the role of PET and PET/computed tomography (CT) in the diagnosis, staging, and follow-up of urological tumours. • A critical, non-structured review of the literature of the role of PET and PET/CT in urological oncology was conducted. • PET and PET/CT can play a role in the management of urological malignancies. For prostate cancer, the advances in radiotracers seems promising, with novel radiotracers yielding better diagnostic and staging results than 18F-fluorodeoxyglucose (18F-FDG). In kidney cancer, PET and PET/CT allow a proper diagnosis before the pathological examination of the surgical specimen. For testis cancer, PET and PET/CT have been shown to be useful in the management of seminoma tumours. In bladder cancer, these scans allow a better initial diagnosis for invasive cancer, while detecting occult metastases. • PET and its combined modality PET/CT have shown their potential in the diagnosis of urological malignancies. However, further studies are needed to establish the role of PET in the management of these diseases. Future applications of PET may involve fusion techniques such as magnetic resonance imaging with PET. © 2010 BJU International.
Keywords: review; cancer staging; nuclear magnetic resonance imaging; positron emission tomography; follow up; radiopharmaceuticals; diagnostic procedure; tomography, x-ray computed; bladder cancer; prostate cancer; urogenital neoplasms; cancer invasion; diagnostic value; fluorodeoxyglucose f 18; computer assisted emission tomography; fluorodeoxyglucose f18; positron-emission tomography; urinary tract cancer; testicular cancer; kidney cancer; testis cancer; pet; acetic acid c 11; choline c 11; seminoma; methionine c 11; occult cancer
Journal Title: BJU International
Volume: 106
Issue: 11
ISSN: 1464-4096
Publisher: Wiley Blackwell  
Date Published: 2010-12-01
Start Page: 1578
End Page: 1593
Language: English
DOI: 10.1111/j.1464-410X.2010.09510.x
PUBMED: 21078036
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 2" - "Export Date: 20 April 2011" - "CODEN: BJINF" - "Source: Scopus"
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