The role of vitamin D in autoimmune thyroid diseases: A narrative review Review


Authors: Czarnywojtek, A.; Florek, E.; Pietrończyk, K.; Sawicka-Gutaj, N.; Ruchała, M.; Ronen, O.; Nixon, I. J.; Shaha, A. R.; Rodrigo, J. P.; Tufano, R. P.; Zafereo, M.; Randolph, G. W.; Ferlito, A.
Review Title: The role of vitamin D in autoimmune thyroid diseases: A narrative review
Abstract: Vitamin D (VitD) deficiency has garnered significant attention in contemporary medical research. Although the canonical biological activity of VitD manifests itself mainly in the regulation of calcium-phosphorus metabolism, recent studies show that, thanks to the presence of numerous receptors, VitD may also play an important role in regulating the immune system. VitD deficiency has been demonstrated to impact autoimmune disease, coeliac disease, infections (including respiratory/COVID-19), and patients with cancer. Recent studies also show that VitD plays a significant role in autoimmune thyroid diseases (AITDs). Many studies have shown a correlation between low VitD levels and chronic autoimmune thyroiditis – Hashimoto thyroiditis (HT), Graves’ disease (GD), and postpartum thyroiditis (PPT). This review article, therefore, describes the current state of knowledge on the role of VitD in AITDs, including HT, GD, and PTT. © 2023 by the authors.
Keywords: vitamin d; graves’ disease; hashimoto thyroiditis; postpartum thyroiditis; riedel thyroiditis
Journal Title: Journal of Clinical Medicine
Volume: 12
Issue: 4
ISSN: 2077-0383
Publisher: MDPI  
Date Published: 2023-02-02
Start Page: 1452
Language: English
DOI: 10.3390/jcm12041452
PROVIDER: scopus
PMCID: PMC9966459
PUBMED: 36835987
DOI/URL:
Notes: Review -- Source: Scopus
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  1. Ashok R Shaha
    697 Shaha