Comparison of a novel thin-walled 25-gauge needle push button blood collection set to a standard 23-gauge needle in a cancer patient population Journal Article
| Authors: | Kirchhoff, D.; Baser, R.; Kwong, D.; Ramanathan, L.; McCash, S. I. |
| Article Title: | Comparison of a novel thin-walled 25-gauge needle push button blood collection set to a standard 23-gauge needle in a cancer patient population |
| Abstract: | BACKGROUND: Phlebotomy can be an uncomfortable and even painful experience that increases in likelihood in patients who require frequent blood draws, such as those with cancer. The 25-gauge BD Vacutainer® UltraTouchTM Push Button Blood Collection Set has a smaller outer bore needle size and unique bevel configuration, which in theory should reduce pain associated with phlebotomy. Smaller needles typically cause less pain, however, they have a higher incidence of compromising the specimen integrity. Innovative engineering allows this particular needle to maintain a larger inner bore size similar to a standard 23-gauge needle. This study compares pain and specimen integrity between this novel device and a standard 23-gauge needle. METHODS: Two cohorts of 190 patients each had phlebotomy performed with either needle. Pain experienced was assessed by patient surveys, rating pain from 0 (low) to 10 (high). Sample integrity was assessed by determining the hemolysis index (Abbott Architect c8000). RESULTS: No statistically significant difference in median pain scores was observed between the 2 cohorts, P-value: 0.068. The 23-gauge cohort more frequently reported 3+ pain than the 25-gauge cohort, 14/190 vs 5/190. Pain scoring 1 and 2 was more frequent in the 25-gauge cohort, 84/190 vs 54/190. Pain scores of 0 were more frequent in the 23-gauge cohort, 122/190 vs 101/190. This stratification is statistically significant, P-value: 0.003. The 25-gauge needle showed no increase in hemolysis rates, P-value: 0.5. CONCLUSIONS: Sample integrity was identical between both needles. The 25-gauge needle resulted in less 3+ pain, while pain scoring 1 and 2 was more frequent in the 25-gauge cohort. © American Association for Clinical Chemistry 2023. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com. |
| Keywords: | neoplasm; neoplasms; pain; hemolysis; needle; needles; adverse event; complication; phlebotomy; humans; human; adverse device effect |
| Journal Title: | Journal of Applied Laboratory Medicine |
| Volume: | 8 |
| Issue: | 2 |
| ISSN: | 2576-9456 |
| Publisher: | Amer Assoc Clinical Chemistry |
| Date Published: | 2023-03-06 |
| Start Page: | 264 |
| End Page: | 271 |
| Language: | English |
| DOI: | 10.1093/jalm/jfac129 |
| PUBMED: | 36680315 |
| PROVIDER: | scopus |
| PMCID: | PMC11066949 |
| DOI/URL: | |
| Notes: | Article -- MSK Cancer Center Support Grant (P30 CA008748) acknowledged in PubMed and PDF -- MSK corresponding author is Samuel McCash -- Source: Scopus |
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13McCash -
77Ramanathan -
2Kwong
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