Reprint of: De novo neuroendocrine features in prostate cancer Review

  


Authors: Abdulfatah, E.; Fine, S. W.; Lotan, T. L.; Mehra, R.
Review Title: Reprint of: De novo neuroendocrine features in prostate cancer
Abstract: Neuroendocrine tumors of the prostate are rare and encompass a group of entities that are classified based on a combination of morphological and immunohistochemical features. Despite the 2016 World Health Organization classification of prostatic neuroendocrine tumors, variants have been reported that do not fit well in the categorization scheme. While the majority of these tumors arise in the setting of castration-resistant prostate cancer (postandrogen deprivation therapy), de novo cases may occur. In this review, we highlight the most significant pathological and immunohistochemical features, emerging biomarkers, and molecular features of such tumors. © 2023
Keywords: pathology; tumor marker; neuroendocrine tumor; prostatic neoplasms; prostate; prostate tumor; carcinoma; neuroendocrine tumors; carcinoma, neuroendocrine; castration resistant prostate cancer; neuroendocrine; transdifferentiation; humans; human; male; prostatic neoplasms, castration-resistant; biomarkers, tumor; de novo; proproliferative
Journal Title: Human Pathology
Volume: 133
ISSN: 0046-8177
Publisher: Elsevier Inc.  
Date Published: 2023-03-01
Start Page: 115
End Page: 125
Language: English
DOI: 10.1016/j.humpath.2023.02.009
PUBMED: 36894369
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85150026818&doi=10.1016%2fj.humpath.2023.02.009&partnerID=40&md5=cef28e772f78ac55d99a4349637f3c88
Notes: Review -- Source: Scopus
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MSK Authors
  1. Samson W Fine
    463 Fine
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