Tumor lysis syndrome: An oncologic emergency Review


Authors: Rivera-Gamma, S.; Davis, M. E.
Review Title: Tumor lysis syndrome: An oncologic emergency
Abstract: Tumor lysis syndrome is an oncologic emergency caused by the release of intracellular material, such as potassium, phosphate, and nucleic acids, into the bloodstream from the disintegration (lysis) of tumor cells. This condition, which is characterized by electrolyte imbalances, can be life-Threatening, causing arrhythmias, seizures, acute kidney injury, and multiple organ failure. The prevention and treatment of tumor lysis syndrome requires immediate recognition of patients at risk for its development. With this knowledge, nurses can better manage and monitor treatments, thereby preventing complications and achieving better patient outcomes. © 2023 Lippincott Williams and Wilkins. All rights reserved.
Keywords: fluid therapy; hyperuricemia; tumor lysis syndrome; hyperkalemia; hemodialysis; metabolic disorder; hypocalcemia; adverse event; renal dialysis; hyperphosphatemia; water-electrolyte imbalance; cancer; humans; human; oncologic emergency
Journal Title: American Journal of Nursing
Volume: 123
Issue: 3
ISSN: 0002-936X
Publisher: Lippincott Williams & Wilkins  
Date Published: 2023-03-01
Start Page: 30
End Page: 35
Language: English
DOI: 10.1097/01.NAJ.0000920996.75505.c2
PUBMED: 36752743
PROVIDER: scopus
DOI/URL:
Notes: Article -- Source: Scopus
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  1. Mary Elizabeth Davis
    49 Davis
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