Melanoma in children and teenagers Book Section


Authors: Brecht, I. B.; Dunkel, I. J.; Garbe, C.
Editors: Balch, C. M.; Atkins, M. B.; Garbe, C.; Gershenwald, J. E.; Halpern, A. C.; Kirkwood, J. M.; McArthur, G. A.; Thompson, J. F.; Sober, A. J.
Article/Chapter Title: Melanoma in children and teenagers
Abstract: Melanoma occurs in all age groups. While under the age of 10 years melanoma is exceedingly rare, increasing numbers are seen within puberty and young adulthood. Under the age of 10 years, melanoma qualifies as an orphan disease, and the annual incidence is <2 per million; no clinical studies exist, evidencebased guidelines for diagnosis and treatment as well as information on biological behavior are scarce. Before puberty, melanoma often presents with atypical amelanotic or raised lesions and does not follow the ABCDE rule. Diagnosis is often challenging as no consensus criteria for “melanocytic tumors of uncertain malignant potential” (MELTUMP), atypical Spitz tumors, and true melanoma do exist. On the other hand, survival and risk factors are similar to those found in adults. While surgical and medical management still follows adult guidelines, there has been a better understanding of specific characteristics of pediatric melanoma, recently. First pediatric clinical studies have been conducted. © Springer Nature Switzerland AG 2020.
Book Title: Cutaneous Melanoma. 6th ed
Volume: 1-2
ISBN: 978-3-030-05068-9
Publisher: Springer  
Publication Place: Cham, Switzerland
Date Published: 2020-01-01
Start Page: 969
End Page: 982
Language: English
DOI: 10.1007/978-3-030-05070-2_16
PROVIDER: scopus
DOI/URL:
Notes: This chapter can be found under "Part VI Uncommon Presentations of Melanoma" -- Source: Scopus
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  1. Ira J Dunkel
    371 Dunkel
  2. Allan C Halpern
    396 Halpern