Not so neutral lipids: Metabolic regulation of the pre-metastatic niche Editorial

  


Authors: Schoenfeld, J. D.; Vardhana, S. A.
Title: Not so neutral lipids: Metabolic regulation of the pre-metastatic niche
Abstract: How primary tumors alter distant tissue sites to facilitate seeding and metastasis remains unclear. In this issue, Gong et al. demonstrate that IL-1β-dependent lipid accumulation in lung mesenchymal cells supports both tumor growth and NK cell dysfunction, facilitating lung metastasis of primary breast tumors. © 2022 Elsevier Inc.
Keywords: primary tumor; unclassified drug; nonhuman; note; mesenchyme cell; interleukin 1beta; cancer cell; natural killer cell; stroma cell; metastatic breast cancer; metabolic regulation; lipid storage; lung alveolus cell; hypoxia inducible lipid droplet associated; lipid droplet associated protein
Journal Title: Cell Metabolism
Volume: 34
Issue: 12
ISSN: 1550-4131
Publisher: Elsevier Inc.  
Date Published: 2022-12-06
Start Page: 1899
End Page: 1900
Language: English
DOI: 10.1016/j.cmet.2022.11.007
PUBMED: 36476931
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85143539103&doi=10.1016%2fj.cmet.2022.11.007&partnerID=40&md5=7000aae81aaf03f894540aedccb9c3c7
Notes: Note -- Export Date: 3 January 2023 -- Source: Scopus
Altmetric
What is Altmetric?
Citation Impact
What is Dimensions Citation Badge?
BMJ Impact Analytics
MSK Authors
  1. Santosha Adipudi Vardhana
    102 Vardhana
  2. Joshua David Schoenfeld
    10 Schoenfeld
Related MSK Work