Pathophysiology and molecular research in lymphedema Book Section
| Authors: | Mehrara, B. J.; Dayan, J. H.; Coriddi, M.; Kataru, R. P. |
| Editors: | Cheng, M. H.; Chang, D. W.; Patel, K. M. |
| Article/Chapter Title: | Pathophysiology and molecular research in lymphedema |
| Abstract: | Secondary lymphedema is the most common long-term complication of cancer treatment and a significant source of morbidity. However, progress in developing novel therapies for lymphedema has been hampered by a lack of detailed understanding of the pathophysiology of the disease. Recent studies have shown that chronic inflammation, fibrosis, and disturbances in lymphangiogenesis play a key role in the development of lymphedema. This chapter will summarize the current understanding of these aspects of secondary lymphedema. © 2022 Elsevier Inc. All rights reserved. |
| Keywords: | inflammation; lymphangiogenesis; lymphedema; fibrosis; factors; molecular mechanisms; risk pathophysiology |
| Book Title: | Principles and Practice of Lymphedema Surgery. 2nd ed |
| ISBN: | 978-0-323-69418-6 |
| Publisher: | Elsevier Inc. |
| Publication Place: | St. Louis, MO |
| Date Published: | 2021-01-01 |
| Start Page: | 23 |
| End Page: | 29 |
| Language: | English |
| DOI: | 10.1016/b978-0-323-69418-6.00004-4 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Book Chapter: 4 -- This chapter can be found under "Section I: Principles of the Lymphatic System" -- Export Date: 3 January 2023 -- Source: Scopus |
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